Leire Ibarz-Escudero

R&D, AstraZeneca
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 10 publications

Enhancing throughput and robustness of the fibroblast to myofibroblast transition assay.

Enhancing throughput and robustness of the fibroblast to myofibroblast transition assay.

Journal: SLAS discovery : advancing life sciences R & D

Published: November 06, 2024

Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice.

Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice.

Journal: Bioorganic & medicinal chemistry letters

Published: August 22, 2023

Highly scalable arrayed CRISPR mediated gene silencing in primary lung small airway epithelial cells.

Highly scalable arrayed CRISPR mediated gene silencing in primary lung small airway epithelial cells.

Journal: SLAS discovery : advancing life sciences R & D

Published: September 05, 2022

Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF.

Sensitization of the UPR by loss of PPP1R15A promotes fibrosis and senescence in IPF.

Journal: Scientific reports

Published: April 30, 2021

Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma.

Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma.

Journal: The Journal of pathology

Published: April 27, 2017

Significant functional difference between TNFAIP3 truncation and missense mutants.

Significant functional difference between TNFAIP3 truncation and missense mutants.

Journal: Haematologica

Published: August 02, 2016

Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

Journal: Nature genetics

Published: May 28, 2016

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

Journal: Nature genetics

Published: October 12, 2015

Somatic Mutation Screening Using Archival Formalin-Fixed, Paraffin-Embedded Tissues by Fluidigm Multiplex PCR and Illumina Sequencing.

Somatic Mutation Screening Using Archival Formalin-Fixed, Paraffin-Embedded Tissues by Fluidigm Multiplex PCR and Illumina Sequencing.

Journal: The Journal of molecular diagnostics : JMD

Published: February 12, 2015

KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype.

KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype.

Journal: Leukemia

Published: June 10, 2014

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Last Updated: 09/26/2026