Lekha Jain
85 Park Rd
Grafton, AUK, New Zealand
Grafton, AUK, New Zealand
Last Updated: 09/26/2026
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Found 12 publications
High glucose upregulates BMAL1 in chondrocytes from macroscopically normal and osteoarthritic human cartilage but this only results in increased collagen synthesis in chondrocytes from macroscopically normal cartilage regions.
Journal: Osteoarthritis and cartilage open
Published: June 16, 2025
Elevated glucose promotes MMP13 and ADAMTS5 production by osteoarthritic chondrocytes under oxygenated but not hypoxic conditions.
Journal: Journal of cellular physiology
Published: October 15, 2023
REST, RCOR1 and RCOR2 expression is reduced in osteoarthritic chondrocytes and contributes to increasing MMP13 and ADAMTS5 expression through upregulating HES1.
Journal: Cellular signalling
Published: May 17, 2023
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes.
Journal: Connective tissue research
Published: May 12, 2023
Phenotype and energy metabolism differ between osteoarthritic chondrocytes from male compared to female patients: Implications for sexual dimorphism in osteoarthritis development?
Journal: Osteoarthritis and cartilage
Published: May 02, 2023
Differential Effects of Hypoxia versus Hyperoxia or Physoxia on Phenotype and Energy Metabolism in Human Chondrocytes from Osteoarthritic Compared to Macroscopically Normal Cartilage.
Journal: International journal of molecular sciences
Published: April 03, 2023
Re-thinking osteoarthritis pathogenesis: what can we learn (and what do we need to unlearn) from mouse models about the mechanisms involved in disease development.
Journal: Arthritis research & therapy
Published: November 25, 2022
The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation.
Journal: Journal of cell communication and signaling
Published: October 08, 2022
IL-1β induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-κB signalling pathways.
Journal: Cellular signalling
Published: July 07, 2021
3D interactions with the growth hormone locus in cellular signalling and cancer-related pathways.
Journal: Journal of molecular endocrinology
Published: February 17, 2020
TNF-α Differentially Regulates Cell Cycle Genes in Promyelocytic and Granulocytic HL-60/S4 Cells.
Journal: G3 (Bethesda, Md.)
Published: July 03, 2019
Showing 1-12 of 12
Last Updated: 09/26/2026