Len R. Stephens

Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 62 publications

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression.

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression.

Journal: Cancer science

Published: March 26, 2026

Phosphoinositide acyl chain diversity: comparative analysis across species and mouse tissues.

Phosphoinositide acyl chain diversity: comparative analysis across species and mouse tissues.

Journal: Biochimica et biophysica acta. Molecular and cell biology of lipids

Published: March 07, 2025

Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling.

Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling.

Journal: PLoS biology

Published: November 02, 2024

FGF-induced phospholipase Cγ signaling regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism.

FGF-induced phospholipase Cγ signaling regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism.

Journal: Cell reports

Published: August 26, 2024

CDS2 expression regulates de novo phosphatidic acid synthesis.

CDS2 expression regulates de novo phosphatidic acid synthesis.

Journal: The Biochemical journal

Published: August 07, 2024

The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling.

The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling.

Journal: Molecular biology of the cell

Published: July 18, 2024

Phospholipase Cγ regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism.

Phospholipase Cγ regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism.

Journal: bioRxiv : the preprint server for biology

Published: July 15, 2024

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types.

Journal: Nature genetics

Published: November 28, 2023

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.

Journal: Molecular cell

Published: September 22, 2022

ARFs get the BioID treatment: what have we been missing?

ARFs get the BioID treatment: what have we been missing?

Journal: The EMBO journal

Published: July 21, 2022

Acyl chain selection couples the consumption and synthesis of phosphoinositides.

Acyl chain selection couples the consumption and synthesis of phosphoinositides.

Journal: The EMBO journal

Published: May 11, 2022

Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models.

Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models.

Journal: The Journal of clinical investigation

Published: February 23, 2022

Showing 1-12 of 62

Last Updated: 09/26/2026