Lena Andersch
Berlin, BE 13353, Germany
Last Updated: 09/26/2026
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Found 10 publications
Investigating genetic modifications to enhance L1CAM-CAR T cell migration in solid tumors in a 3D bioprinted neuroblastoma model.
Journal: Frontiers in immunology
Published: July 31, 2025
Personalized CRISPR knock-in cytokine gene therapy to remodel the tumor microenvironment and enhance CAR T cell therapy in solid tumors.
Journal: Nature communications
Published: April 01, 2025
Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy.
Journal: Pharmacological research
Published: October 20, 2024
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells.
Journal: bioRxiv : the preprint server for biology
Published: December 20, 2023
Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells.
Journal: Blood
Published: April 26, 2023
Combination of GD2-directed bispecific trifunctional antibody therapy with Pd-1 immune checkpoint blockade induces anti-neuroblastoma immunity in a syngeneic mouse model.
Journal: Frontiers in immunology
Published: August 19, 2022
Inhibiting Lysine Demethylase 1A Improves L1CAM-Specific CAR T Cell Therapy by Unleashing Antigen-Independent Killing via the FAS-FASL Axis.
Journal: Cancers
Published: September 27, 2021
GD2-directed bispecific trifunctional antibody outperforms dinutuximab beta in a murine model for aggressive metastasized neuroblastoma.
Journal: Journal for immunotherapy of cancer
Published: June 18, 2021
A Reproducible Bioprinted 3D Tumor Model Serves as a Preselection Tool for CAR T Cell Therapy Optimization.
Journal: Frontiers in immunology
Published: April 01, 2021
Showing 1-10 of 10
Last Updated: 09/26/2026