Lena Erkert

Erlangen, BY, Germany

Last Updated: 09/26/2026

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Found 19 publications

Paneth cells as orchestrators of epithelial barrier defense and emerging therapeutic targets in inflammatory bowel disease.

Paneth cells as orchestrators of epithelial barrier defense and emerging therapeutic targets in inflammatory bowel disease.

Journal: Seminars in immunopathology
Published: November 25, 2025

Coordinated Interferon-γ/Tumor Necrosis Factor Axis Drives Selective Loss of Activated Enteric Glia in Inflammatory Bowel Diseases.

Coordinated Interferon-γ/Tumor Necrosis Factor Axis Drives Selective Loss of Activated Enteric Glia in Inflammatory Bowel Diseases.

Journal: Cellular and molecular gastroenterology and hepatology
Published: June 03, 2025

Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.

Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.

Journal: Science translational medicine
Published: January 15, 2025

Pharmacological inhibitors of the gamma-secretase enzyme complex disrupt epithelial cell function triggering colitis in mice.

Pharmacological inhibitors of the gamma-secretase enzyme complex disrupt epithelial cell function triggering colitis in mice.

Journal: Journal of Crohn's & colitis
Published: December 13, 2024

Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD.

Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD.

Journal: Gut
Published: August 26, 2024

Intestinal epithelial Gasdermin C is induced by IL-4R/STAT6 signaling but is dispensable for gut immune homeostasis.

Intestinal epithelial Gasdermin C is induced by IL-4R/STAT6 signaling but is dispensable for gut immune homeostasis.

Journal: Scientific reports
Published: June 19, 2024

TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice.

TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice.

Journal: Mucosal immunology
Published: June 10, 2024

Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis.

Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis.

Journal: Gut
Published: November 24, 2023

Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease.

Know your neighbors: microbial recognition at the intestinal barrier and its implications for gut homeostasis and inflammatory bowel disease.

Journal: Frontiers in cell and developmental biology
Published: May 24, 2023

Analysis of the interferon-γ-induced secretome of intestinal endothelial cells: putative impact on epithelial barrier dysfunction in IBD.

Analysis of the interferon-γ-induced secretome of intestinal endothelial cells: putative impact on epithelial barrier dysfunction in IBD.

Journal: Frontiers in cell and developmental biology
Published: May 22, 2023

IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.

IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling.

Journal: Gut
Published: February 05, 2023

Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling.

Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling.

Journal: Gut
Published: March 08, 2022
Showing 1-12 of 19

Last Updated: 09/26/2026