Lennart Mucke

Neurology
1650 Owens St
San Francisco, CA 94158

Last Updated: 09/26/2026

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Found 53 publications

Tau reduction counteracts transcriptomic and behavioral abnormalities in an Alzheimer amyloid model.

Tau reduction counteracts transcriptomic and behavioral abnormalities in an Alzheimer amyloid model.

Journal: bioRxiv : the preprint server for biology
Published: August 20, 2026

Author Correction: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.

Author Correction: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.

Journal: EMBO reports
Published: October 03, 2024

CHOIR improves significance-based detection of cell types and states from single-cell data.

CHOIR improves significance-based detection of cell types and states from single-cell data.

Journal: bioRxiv : the preprint server for biology
Published: February 08, 2024

CHOIR improves significance-based detection of cell types and states from single-cell data.

CHOIR improves significance-based detection of cell types and states from single-cell data.

Journal: Nature genetics
Published: December 22, 2023

Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.

Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.

Journal: Neurobiology of disease
Published: May 12, 2023

TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model.

TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model.

Journal: Science translational medicine
Published: April 27, 2022

Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial.

Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial.

Journal: JAMA neurology
Published: September 27, 2021

Interdependence of neural network dysfunction and microglial alterations in Alzheimer's disease-related models.

Interdependence of neural network dysfunction and microglial alterations in Alzheimer's disease-related models.

Journal: iScience
Published: August 20, 2021

Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.

Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.

Journal: Cell reports
Published: April 01, 2021

Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.

Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.

Journal: eNeuro
Published: March 03, 2021

Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies.

Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies.

Journal: Science (New York, N.Y.)
Published: February 26, 2021

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit.

Journal: eLife
Published: April 18, 2020
Showing 1-12 of 53

Last Updated: 09/26/2026