Leo S. Price

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 24 publications

Targeted analysis of salicylate binding partners in renal epithelial cells reveals major AMPK dependency.

Targeted analysis of salicylate binding partners in renal epithelial cells reveals major AMPK dependency.

Journal: Biochimica et biophysica acta. Molecular cell research
Published: March 03, 2025

Ex vivo 3D micro-tumour testing platform for predicting clinical response to platinum-based therapy in patients with high-grade serous ovarian cancer.

Ex vivo 3D micro-tumour testing platform for predicting clinical response to platinum-based therapy in patients with high-grade serous ovarian cancer.

Journal: NPJ precision oncology
Published: January 03, 2025

A Patient-Derived 3D Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates.

A Patient-Derived 3D Cyst Model of Polycystic Kidney Disease That Mimics Disease Development and Responds to Repurposing Candidates.

Journal: Clinical and translational science
Published: October 30, 2024

A 3D human co-culture to model neuron-astrocyte interactions in tauopathies.

A 3D human co-culture to model neuron-astrocyte interactions in tauopathies.

Journal: Biological procedures online
Published: September 02, 2022

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.

Differential reprogramming of breast cancer subtypes in 3D cultures and implications for sensitivity to targeted therapy.

Journal: Scientific reports
Published: October 03, 2020

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.

Journal: Nature cancer
Published: August 10, 2020

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.

Journal: PloS one
Published: November 01, 2019

Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective.

Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective.

Journal: Scientific reports
Published: October 28, 2019

Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles.

Prioritization of novel ADPKD drug candidates from disease-stage specific gene expression profiles.

Journal: EBioMedicine
Published: September 13, 2019

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis.

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis.

Journal: SLAS discovery : advancing life sciences R & D
Published: March 01, 2019

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.

High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability.

Journal: Archives of toxicology
Published: November 09, 2018

In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease.

In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease.

Journal: Journal of molecular cell biology
Published: June 17, 2018
Showing 1-12 of 24

Last Updated: 09/26/2026