Leon G. Coleman

Vascular Surgery

101 Manning Dr
Chapel Hill, NC 27514

Last Updated: 09/26/2026

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Found 47 publications

INTERFERON-REGULATORY FACTOR 7: A NEUROIMMUNE ROLE FOR VAPOR-INDUCED ESCALATIONS IN ETHANOL SELF-ADMINISTRATION.

INTERFERON-REGULATORY FACTOR 7: A NEUROIMMUNE ROLE FOR VAPOR-INDUCED ESCALATIONS IN ETHANOL SELF-ADMINISTRATION.

Journal: bioRxiv : the preprint server for biology

Published: April 10, 2026

Microglia promote neurodegeneration and hyperkatifeia during withdrawal and prolonged abstinence from binge alcohol.

Microglia promote neurodegeneration and hyperkatifeia during withdrawal and prolonged abstinence from binge alcohol.

Journal: bioRxiv : the preprint server for biology

Published: September 18, 2025

Alcohol use reduces the efficacy of anti-PD1 immunotherapy by disrupting anti-tumor immunity.

Alcohol use reduces the efficacy of anti-PD1 immunotherapy by disrupting anti-tumor immunity.

Journal: bioRxiv : the preprint server for biology

Published: July 30, 2025

Xylazine and fentanyl co-administration delays wound healing in mice.

Xylazine and fentanyl co-administration delays wound healing in mice.

Journal: bioRxiv : the preprint server for biology

Published: July 16, 2025

Microglia Promote Neurodegeneration and Hyperkatifeia during Withdrawal and Abstinence from Binge Alcohol.

Microglia Promote Neurodegeneration and Hyperkatifeia during Withdrawal and Abstinence from Binge Alcohol.

Journal: The American journal of pathology

Published: April 30, 2025

Cortical reactive microglia activate astrocytes, increasing neurodegeneration in human alcohol use disorder.

Cortical reactive microglia activate astrocytes, increasing neurodegeneration in human alcohol use disorder.

Journal: Brain, behavior, and immunity

Published: April 25, 2025

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.

Journal: bioRxiv : the preprint server for biology

Published: April 01, 2025

Excessive Alcohol Use as a Risk Factor for Alzheimer's Disease: Epidemiological and Preclinical Evidence.

Excessive Alcohol Use as a Risk Factor for Alzheimer's Disease: Epidemiological and Preclinical Evidence.

Journal: Advances in experimental medicine and biology

Published: March 25, 2025

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.

Journal: Frontiers in immunology

Published: March 19, 2025

Loss of lysosomal acid lipase contributes to Alzheimer's disease pathology and cognitive decline.

Loss of lysosomal acid lipase contributes to Alzheimer's disease pathology and cognitive decline.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: March 12, 2025

Adolescent binge alcohol exposure accelerates Alzheimer's disease-associated basal forebrain neuropathology through proinflammatory HMGB1 signaling.

Adolescent binge alcohol exposure accelerates Alzheimer's disease-associated basal forebrain neuropathology through proinflammatory HMGB1 signaling.

Journal: Frontiers in aging neuroscience

Published: November 20, 2024

Utilizing blood inflammatory markers in alcohol studies: Considerations and recommendations for study design, sample collection, and data analysis.

Utilizing blood inflammatory markers in alcohol studies: Considerations and recommendations for study design, sample collection, and data analysis.

Journal: Neuroscience and biobehavioral reviews

Published: October 17, 2024

Showing 1-12 of 47

Last Updated: 09/26/2026