Ley-fang F. Kua

1E Kent Ridge Road
Singapore, Singapore

Last Updated: 09/26/2026

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Found 15 publications

KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity.

KDM6A Depletion in Breast Epithelial Cells Leads to Reduced Sensitivity to Anticancer Agents and Increased TGFβ Activity.

Journal: Molecular cancer research : MCR

Published: May 28, 2021

Chemoradiation induces upregulation of immunogenic cell death-related molecules together with increased expression of PD-L1 and galectin-9 in gastric cancer.

Chemoradiation induces upregulation of immunogenic cell death-related molecules together with increased expression of PD-L1 and galectin-9 in gastric cancer.

Journal: Scientific reports

Published: February 23, 2021

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.

Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Published: August 18, 2020

Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.

Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.

Journal: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association

Published: January 20, 2020

Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.

Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.

Journal: International journal of oncology

Published: October 05, 2018

Implication of Highly Cytotoxic Natural Killer Cells for Esophageal Squamous Cell Carcinoma Treatment.

Implication of Highly Cytotoxic Natural Killer Cells for Esophageal Squamous Cell Carcinoma Treatment.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997)

Published: April 24, 2018

A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer.

A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer.

Journal: BMC cancer

Published: October 27, 2017

PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer.

PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer.

Journal: Cancer science

Published: August 04, 2017

Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress.

Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress.

Journal: Cancer immunology, immunotherapy : CII

Published: May 28, 2016

Accumulation of CD11c+CD163+ Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity.

Accumulation of CD11c+CD163+ Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: May 24, 2016

Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility.

Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility.

Journal: Journal of gastroenterology

Published: September 08, 2015

Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.

Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.

Journal: Cancer science

Published: June 02, 2014

Showing 1-12 of 15

Last Updated: 09/26/2026