Li-hua Zhao
State Key Laboratory Of Medical Genomics
Shanghai, 200025, China
Shanghai, 200025, China
Last Updated: 09/26/2026
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Found 17 publications
Structural basis of β-arrestin coupling and transducer selectivity in PAC1R.
Journal: Acta pharmacologica Sinica
Published: June 24, 2026
Structural basis for lysophosphatidic acid recognition and atypical Gαq coupling by LPAR5.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 18, 2026
N-terminally modified GLP1R agonists drive G protein bias via extracellular loop 3 displacement.
Journal: Cell reports
Published: January 17, 2026
Arrestins as programmable integrators of GPCR signaling: structural microstates, spatiotemporal logic, and therapeutic control.
Journal: Cell discovery
Published: December 27, 2025
Structural insights into nonpeptide antagonist inhibition of somatostatin receptor subtype 5.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 19, 2025
Structural basis of PTH1R-β-arrestin core engagement reveals design principles for G-protein-biased therapeutics.
Journal: Nature structural & molecular biology
Published: July 31, 2025
Molecular basis for cross-activation of NPFF2R by a short PrRP-related peptide.
Journal: Acta pharmacologica Sinica
Published: July 14, 2025
Structural and mechanistic insights into dual activation of cagrilintide in amylin and calcitonin receptors.
Journal: Acta pharmacologica Sinica
Published: May 07, 2025
Constitutive signal bias mediated by the human GHRHR splice variant 1.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 17, 2021
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Journal: Cell research
Published: August 24, 2020
Structural basis for activation of the growth hormone-releasing hormone receptor.
Journal: Nature communications
Published: June 04, 2020
Structure and dynamics of the active human parathyroid hormone receptor-1.
Journal: Science (New York, N.Y.)
Published: October 20, 2018
Last Updated: 09/26/2026