Li-hui Xu

State Key Laboratory Of Bioactive Molecules And Druggability Assessment
Guangzhou, 510632, China

Last Updated: 09/26/2026

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Found 45 publications

Baicalin inhibits PANoptosis by blocking mitochondrial Z-DNA formation and ZBP1-PANoptosome assembly in macrophages.

Baicalin inhibits PANoptosis by blocking mitochondrial Z-DNA formation and ZBP1-PANoptosome assembly in macrophages.

Journal: Acta pharmacologica Sinica

Published: March 28, 2024

Scutellarin inhibits inflammatory PANoptosis by diminishing mitochondrial ROS generation and blocking PANoptosome formation.

Scutellarin inhibits inflammatory PANoptosis by diminishing mitochondrial ROS generation and blocking PANoptosome formation.

Journal: International immunopharmacology

Published: March 23, 2024

Inflammatory cell death PANoptosis is induced by the anti-cancer curaxin CBL0137 via eliciting the assembly of ZBP1-associated PANoptosome.

Inflammatory cell death PANoptosis is induced by the anti-cancer curaxin CBL0137 via eliciting the assembly of ZBP1-associated PANoptosome.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Published: December 16, 2023

Triptolide induces PANoptosis in macrophages and causes organ injury in mice.

Triptolide induces PANoptosis in macrophages and causes organ injury in mice.

Journal: Apoptosis : an international journal on programmed cell death

Published: August 21, 2023

Anti-Necroptotic Effects of Itaconate and its Derivatives.

Anti-Necroptotic Effects of Itaconate and its Derivatives.

Journal: Inflammation

Published: June 19, 2023

Blocking reverse electron transfer-mediated mitochondrial DNA oxidation rescues cells from PANoptosis.

Blocking reverse electron transfer-mediated mitochondrial DNA oxidation rescues cells from PANoptosis.

Journal: Acta pharmacologica Sinica

Published: May 15, 2023

Celastrol inhibits necroptosis by attenuating the RIPK1/RIPK3/MLKL pathway and confers protection against acute pancreatitis in mice.

Celastrol inhibits necroptosis by attenuating the RIPK1/RIPK3/MLKL pathway and confers protection against acute pancreatitis in mice.

Journal: International immunopharmacology

Published: December 04, 2022

Theaflavin mitigates acute gouty peritonitis and septic organ injury in mice by suppressing NLRP3 inflammasome assembly.

Theaflavin mitigates acute gouty peritonitis and septic organ injury in mice by suppressing NLRP3 inflammasome assembly.

Journal: Acta pharmacologica Sinica

Published: November 30, 2022

Baicalin inhibits necroptosis by decreasing oligomerization of phosphorylated MLKL and mitigates caerulein-induced acute pancreatitis in mice.

Baicalin inhibits necroptosis by decreasing oligomerization of phosphorylated MLKL and mitigates caerulein-induced acute pancreatitis in mice.

Journal: International immunopharmacology

Published: March 10, 2022

Taraxasterol mitigates Con A-induced hepatitis in mice by suppressing interleukin-2 expression and its signaling in T lymphocytes.

Taraxasterol mitigates Con A-induced hepatitis in mice by suppressing interleukin-2 expression and its signaling in T lymphocytes.

Journal: International immunopharmacology

Published: July 15, 2021

Injection of Escherichia coli to Induce Sepsis.

Injection of Escherichia coli to Induce Sepsis.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: May 28, 2021

Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways.

Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways.

Journal: Acta pharmacologica Sinica

Published: April 03, 2021

Showing 1-12 of 45

Last Updated: 09/26/2026