Li-li Xu

639 Longmian Avenue
Nanjing, 211198, China

Last Updated: 09/26/2026

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Found 27 publications

Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis.

Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis.

Journal: Journal of medicinal chemistry

Published: June 18, 2024

Identification and Validation of PKR as a Direct Target for the Novel Sulfonamide-Substituted Tetrahydroquinoline Nonselective Inhibitor of the NLRP3 Inflammasome.

Identification and Validation of PKR as a Direct Target for the Novel Sulfonamide-Substituted Tetrahydroquinoline Nonselective Inhibitor of the NLRP3 Inflammasome.

Journal: Journal of medicinal chemistry

Published: June 10, 2024

Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor.

Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor.

Journal: Environmental toxicology

Published: November 03, 2023

Mechanisms of NLRP3 inflammasome activation and the development of peptide inhibitors.

Mechanisms of NLRP3 inflammasome activation and the development of peptide inhibitors.

Journal: Cytokine & growth factor reviews

Published: September 22, 2023

Protein-protein interactions and related inhibitors involved in the NLRP3 inflammasome pathway.

Protein-protein interactions and related inhibitors involved in the NLRP3 inflammasome pathway.

Journal: Cytokine & growth factor reviews

Published: September 12, 2023

Recent advances in the treatment of IBD: Targets, mechanisms and related therapies.

Recent advances in the treatment of IBD: Targets, mechanisms and related therapies.

Journal: Cytokine & growth factor reviews

Published: May 04, 2023

Short-term antithrombotic strategies after left atrial appendage occlusion: a systematic review and network meta-analysis.

Short-term antithrombotic strategies after left atrial appendage occlusion: a systematic review and network meta-analysis.

Journal: Frontiers in pharmacology

Published: February 06, 2023

Discovery of a Series of 5-Amide-1H-pyrazole-3-carboxyl Derivatives as Potent P2Y14R Antagonists with Anti-Inflammatory Characters.

Discovery of a Series of 5-Amide-1H-pyrazole-3-carboxyl Derivatives as Potent P2Y14R Antagonists with Anti-Inflammatory Characters.

Journal: Journal of medicinal chemistry

Published: November 17, 2022

Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.

Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome.

Journal: Journal of medicinal chemistry

Published: March 07, 2022

The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies.

The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies.

Journal: Cytokine & growth factor reviews

Published: March 23, 2021

Advances in Cryochemistry: Mechanisms, Reactions and Applications.

Advances in Cryochemistry: Mechanisms, Reactions and Applications.

Journal: Molecules (Basel, Switzerland)

Published: January 19, 2021

Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis.

Development of Novel Tetrahydroquinoline Inhibitors of NLRP3 Inflammasome for Potential Treatment of DSS-Induced Mouse Colitis.

Journal: Journal of medicinal chemistry

Published: December 17, 2020

Showing 1-12 of 27

Last Updated: 09/26/2026