Li Lu
Calgary, AB, Canada
Last Updated: 09/26/2026
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Found 13 publications
Contrasting roles of autophagy in cellular prion infection.
Journal: Autophagy
Published: August 09, 2025
Design, Synthesis, and Biological Evaluation of Novel Chromanone Derivatives as Multifunctional Agents for the Treatment of Alzheimer's Disease.
Journal: ACS chemical neuroscience
Published: November 16, 2022
Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolism.
Journal: The Journal of biological chemistry
Published: August 24, 2022
Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease.
Journal: European journal of medicinal chemistry
Published: July 31, 2022
New Insights into Neuroinflammation Involved in Pathogenic Mechanism of Alzheimer's Disease and Its Potential for Therapeutic Intervention.
Journal: Cells
Published: May 01, 2022
Novel and Potent Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease from Natural (±)-7,8-Dihydroxy-3-methyl-isochroman-4-one.
Journal: Molecules (Basel, Switzerland)
Published: April 12, 2022
Correction: Disulfide-crosslink scanning reveals prion-induced conformational changes and prion strain-specific structures of the pathological prion protein PrPSc.
Journal: The Journal of biological chemistry
Published: September 23, 2018
Overexpression of quality control proteins reduces prion conversion in prion-infected cells.
Journal: The Journal of biological chemistry
Published: March 07, 2018
Disulfide-crosslink scanning reveals prion-induced conformational changes and prion strain-specific structures of the pathological prion protein PrPSc.
Journal: The Journal of biological chemistry
Published: December 22, 2017
The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions.
Journal: Scientific reports
Published: July 17, 2017
Immunization of cervidized transgenic mice with multimeric deer prion protein induces self-antibodies that antagonize chronic wasting disease infectivity in vitro.
Journal: Scientific reports
Published: June 07, 2017
Last Updated: 09/26/2026