Li Zheng

Holistic Medicine

475 Hillside Ave
Needham, MA 02494

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 55 publications

PARP1-mediated 5' flap dynamics facilitate Okazaki fragment maturation.

PARP1-mediated 5' flap dynamics facilitate Okazaki fragment maturation.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2026

Rapid Optimization Enabled by Single-Molecule Tracking: Discovery of a Potent RUVBL1/2 Inhibitor to Evaluate the Targeting of MYC-Driven Cancers.

Rapid Optimization Enabled by Single-Molecule Tracking: Discovery of a Potent RUVBL1/2 Inhibitor to Evaluate the Targeting of MYC-Driven Cancers.

Journal: Journal of medicinal chemistry

Published: April 22, 2026

Biochemical characterization of MIF nuclease with a FRET-based quantitative 3' nuclease assay.

Biochemical characterization of MIF nuclease with a FRET-based quantitative 3' nuclease assay.

Journal: Analytical biochemistry

Published: December 23, 2025

Oncometabolite fumarate impairs ATR-CHK1 signaling by succinating RPA1 in Fumarate Hydratase-deficient renal cell carcinoma cells.

Oncometabolite fumarate impairs ATR-CHK1 signaling by succinating RPA1 in Fumarate Hydratase-deficient renal cell carcinoma cells.

Journal: bioRxiv : the preprint server for biology

Published: December 22, 2025

JMJD1B-mediated FEN1 demethylation allows timely switching of Okazaki fragment maturation core enzymes to avoid mutagenic flap ligation by PARP1-LIG3.

JMJD1B-mediated FEN1 demethylation allows timely switching of Okazaki fragment maturation core enzymes to avoid mutagenic flap ligation by PARP1-LIG3.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

XPF mediates 3' flap processing for FEN1-independent Okazaki fragment maturation.

XPF mediates 3' flap processing for FEN1-independent Okazaki fragment maturation.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

XPF mediates 3' flap processing for FEN1-independent Okazaki fragment maturation.

XPF mediates 3' flap processing for FEN1-independent Okazaki fragment maturation.

Journal: Nucleic acids research

Published: October 31, 2025

DNA Replication Errors Drive Genome-Wide Small Inverted Triplication Dynamics.

DNA Replication Errors Drive Genome-Wide Small Inverted Triplication Dynamics.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 31, 2025

Oncometabolite fumarate impairs ATR-CHK1 signaling by succinating RPA1 in fumarate hydratase-deficient renal cell carcinoma cells.

Oncometabolite fumarate impairs ATR-CHK1 signaling by succinating RPA1 in fumarate hydratase-deficient renal cell carcinoma cells.

Journal: Cancer & metabolism

Published: October 17, 2025

Adaptive Regulation of dNTP Homeostasis Confers Osimertinib Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma.

Adaptive Regulation of dNTP Homeostasis Confers Osimertinib Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma.

Journal: Cancer research

Published: July 25, 2025

Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy.

Discovery and Characterization of Small Molecule Inhibitors Targeting Exonuclease 1 for Homologous Recombination-Deficient Cancer Therapy.

Journal: ACS chemical biology

Published: May 16, 2025

DNA2 and MSH2 activity collectively mediate chemically stabilized G4 for efficient telomere replication.

DNA2 and MSH2 activity collectively mediate chemically stabilized G4 for efficient telomere replication.

Journal: bioRxiv : the preprint server for biology

Published: May 07, 2025

Showing 1-12 of 55

Last Updated: 09/26/2026