Liam M. Ferguson

Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

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Found 13 publications

Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery.

Humanization of Drug Metabolism in the Plasmodium berghei Mouse Model for Antimalarial Drug Discovery.

Journal: ACS infectious diseases
Published: December 01, 2025

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens.

Rational Exploration of 2,4-Diaminopyrimidines as DHFR Inhibitors Active against Mycobacterium abscessus and Mycobacterium avium, Two Emerging Human Pathogens.

Journal: Journal of medicinal chemistry
Published: October 29, 2024

Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.

Cryptosporidium lysyl-tRNA synthetase inhibitors define the interplay between solubility and permeability required to achieve efficacy.

Journal: Science translational medicine
Published: October 23, 2024

Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.

Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 05, 2024

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Journal: Journal of medicinal chemistry
Published: July 28, 2023

The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes.

The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes.

Journal: Microbial cell (Graz, Austria)
Published: August 19, 2022

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Journal: European journal of medicinal chemistry
Published: February 15, 2022

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: April 10, 2019

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 22, 2019

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).

Journal: ACS medicinal chemistry letters
Published: December 07, 2018

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.

Journal: Journal of medicinal chemistry
Published: June 27, 2018

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.

Journal: ACS infectious diseases
Published: March 10, 2018
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Last Updated: 09/26/2026