Liang Xiong

State Key Laboratory Of Discovery And Utilization Of Functional Components In Traditional Chinese Medicine
Guiyang, 550014, China

Last Updated: 09/26/2026

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Found 11 publications

Corrigendum to "Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer" [J. Adv. Res. 84 (2026) 1105-1126].

Corrigendum to "Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer" [J. Adv. Res. 84 (2026) 1105-1126].

Journal: Journal of advanced research

Published: August 17, 2026

Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor.

Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor.

Journal: Bioorganic & medicinal chemistry

Published: September 05, 2025

Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.

Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.

Journal: Journal of advanced research

Published: June 05, 2025

Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.

Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.

Journal: Journal of advanced research

Published: June 05, 2025

A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.

A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.

Journal: Bioorganic chemistry

Published: February 07, 2025

Design and synthesis of novel derivatives of bisepoxylignans as potent anti-inflammatory agents involves the modulation of the M1/M2 microglia phenotype via TLR4/NF-κB signaling pathway.

Design and synthesis of novel derivatives of bisepoxylignans as potent anti-inflammatory agents involves the modulation of the M1/M2 microglia phenotype via TLR4/NF-κB signaling pathway.

Journal: European journal of medicinal chemistry

Published: May 25, 2024

Synthesis and antitumor activities of novel 3-(6-aminopyridin-3-yl)benzamide derivatives: Inducing cell cycle arrest and apoptosis via AURKB transcription inhibition.

Synthesis and antitumor activities of novel 3-(6-aminopyridin-3-yl)benzamide derivatives: Inducing cell cycle arrest and apoptosis via AURKB transcription inhibition.

Journal: Bioorganic chemistry

Published: April 07, 2024

Design, Synthesis and Biological Evaluation of 6-(Imidazo[1,2-a]pyridin-6-yl)quinazoline Derivatives as Anticancer Agents via PI3Kα Inhibition.

Design, Synthesis and Biological Evaluation of 6-(Imidazo[1,2-a]pyridin-6-yl)quinazoline Derivatives as Anticancer Agents via PI3Kα Inhibition.

Journal: International journal of molecular sciences

Published: February 15, 2023

Design, synthesis, and biological evaluation of 6-(imidazo[1,2-a] pyridin-6-yl) quinazolin-4(3H)-one derivatives as potent anticancer agents by dual targeting Aurora kinase and ROR1.

Design, synthesis, and biological evaluation of 6-(imidazo[1,2-a] pyridin-6-yl) quinazolin-4(3H)-one derivatives as potent anticancer agents by dual targeting Aurora kinase and ROR1.

Journal: Bioorganic chemistry

Published: December 31, 2022

Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.

Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H2O2-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.

Journal: Antioxidants (Basel, Switzerland)

Published: September 22, 2022

Structure optimization, synthesis, and biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)-quinazolin-4(3H)-one derivatives as potential multi-targeted anticancer agents via Aurora A/ PI3K/BRD4 inhibition.

Structure optimization, synthesis, and biological evaluation of 6-(2-amino-1H-benzo[d]imidazole-6-yl)-quinazolin-4(3H)-one derivatives as potential multi-targeted anticancer agents via Aurora A/ PI3K/BRD4 inhibition.

Journal: Bioorganic chemistry

Published: August 25, 2022

Showing 1-11 of 11

Last Updated: 09/26/2026