Libor Macurek

Prague, PR 14220, Czech Republic

Last Updated: 09/26/2026

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Found 56 publications

Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification.

Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification.

Journal: Cancer cell international

Published: December 11, 2025

Changes in the approach to the analysis and evaluation of inherited pathogenic TP53 variants.

Changes in the approach to the analysis and evaluation of inherited pathogenic TP53 variants.

Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti

Published: October 30, 2025

Case-Control Study for 23 Cancer Types With Functional Analysis of CHEK2: Risk Estimation and Clinical Recommendations in East Asia.

Case-Control Study for 23 Cancer Types With Functional Analysis of CHEK2: Risk Estimation and Clinical Recommendations in East Asia.

Journal: JCO precision oncology

Published: September 02, 2025

An ATM-PPM1D Circuit Controls the Processing and Restart of DNA Replication Forks.

An ATM-PPM1D Circuit Controls the Processing and Restart of DNA Replication Forks.

Journal: bioRxiv : the preprint server for biology

Published: June 04, 2025

Distinct mechanisms of replication stress induced by oncogenic RAS and cyclin E1 converge on R-loop-dependent fork reversal.

Distinct mechanisms of replication stress induced by oncogenic RAS and cyclin E1 converge on R-loop-dependent fork reversal.

Journal: Nature communications

Published: March 19, 2025

In-frame germline TP53 variant impairs p53 oligomerization and predisposes to cancer.

In-frame germline TP53 variant impairs p53 oligomerization and predisposes to cancer.

Journal: Scientific reports

Published: December 26, 2024

FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton.

FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 12, 2024

Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models.

Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models.

Journal: Communications biology

Published: June 27, 2024

PPM1D activity promotes cellular transformation by preventing senescence and cell death.

PPM1D activity promotes cellular transformation by preventing senescence and cell death.

Journal: Oncogene

Published: May 02, 2024

Hematopoietic stem cell fate under the influence of Ser/Thr protein phosphatases.

Hematopoietic stem cell fate under the influence of Ser/Thr protein phosphatases.

Journal: Haematologica

Published: February 22, 2024

MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesis.

MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesis.

Journal: Nature communications

Published: February 15, 2024

A comprehensive study evaluating germline FANCG variants in predisposition to breast and ovarian cancer.

A comprehensive study evaluating germline FANCG variants in predisposition to breast and ovarian cancer.

Journal: Cancer medicine

Published: February 15, 2024

Showing 1-12 of 56

Last Updated: 09/26/2026