Lihui Wang

No.103 Wenhua Road
Shenyang, 110016, China

Last Updated: 09/26/2026

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Found 85 publications

4-Arylindolines Bearing a Pyrido[3,2-d]pyrimidine Scaffold as Dual Inhibitors of the PD-1/PD-L1 Interaction and NAMPT for Targeting Tumor Immunoevasion and Metabolism.

4-Arylindolines Bearing a Pyrido[3,2-d]pyrimidine Scaffold as Dual Inhibitors of the PD-1/PD-L1 Interaction and NAMPT for Targeting Tumor Immunoevasion and Metabolism.

Journal: Journal of medicinal chemistry

Published: June 29, 2026

Tumor immune microenvironment facilitates resistance to KRAS G12C inhibitor sotorasib by altered PD-L1 expression.

Tumor immune microenvironment facilitates resistance to KRAS G12C inhibitor sotorasib by altered PD-L1 expression.

Journal: Journal for immunotherapy of cancer

Published: January 20, 2026

Novel Isoidide Subunit-Containing Xanthine Oxidase Inhibitors with Potent Hypouricemic Effects.

Novel Isoidide Subunit-Containing Xanthine Oxidase Inhibitors with Potent Hypouricemic Effects.

Journal: Journal of medicinal chemistry

Published: November 28, 2025

Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer.

Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 30, 2025

Discovery of Pyrazole-Containing 4‑Arylindolines as Potent Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Discovery of Pyrazole-Containing 4‑Arylindolines as Potent Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction.

Journal: ACS medicinal chemistry letters

Published: July 09, 2025

Design and synthesis of Prostanoid EP4 receptor antagonists for treatment of inflammatory pain.

Design and synthesis of Prostanoid EP4 receptor antagonists for treatment of inflammatory pain.

Journal: Bioorganic chemistry

Published: July 08, 2025

Protein acylations in cancer immunity: effects and therapeutic opportunities.

Protein acylations in cancer immunity: effects and therapeutic opportunities.

Journal: Trends in pharmacological sciences

Published: March 05, 2025

Identifying KDM5B as the synthetic lethal target of KMT2D-mutated osteosarcoma.

Identifying KDM5B as the synthetic lethal target of KMT2D-mutated osteosarcoma.

Journal: Chemico-biological interactions

Published: October 28, 2024

Discovery of Novel Non-nucleoside DOT1LR231Q Inhibitors with Improved Pharmacokinetic Properties and Anti-lung Cancer Efficacy.

Discovery of Novel Non-nucleoside DOT1LR231Q Inhibitors with Improved Pharmacokinetic Properties and Anti-lung Cancer Efficacy.

Journal: Journal of medicinal chemistry

Published: September 10, 2024

Identification of an m6A Natural Inhibitor, Lobeline, That Reverses Lenvatinib Resistance in Hepatocellular Tumors.

Identification of an m6A Natural Inhibitor, Lobeline, That Reverses Lenvatinib Resistance in Hepatocellular Tumors.

Journal: Journal of natural products

Published: August 13, 2024

Progressive Dual Priori Network for Generalized Breast Tumor Segmentation.

Progressive Dual Priori Network for Generalized Breast Tumor Segmentation.

Journal: IEEE journal of biomedical and health informatics

Published: June 06, 2024

Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR-Mutant Non-Small Cell Lung Cancer.

Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR-Mutant Non-Small Cell Lung Cancer.

Journal: Cancer research

Published: May 31, 2024

Showing 1-12 of 85

Last Updated: 09/26/2026