Lilian Lee

Toronto, ON M5G0A4, Canada

Last Updated: 09/26/2026

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Found 14 publications

OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma.

OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma.

Journal: Nature communications
Published: May 18, 2023

Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions.

Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions.

Journal: Nature communications
Published: May 05, 2021

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.

Journal: Nature cancer
Published: April 03, 2020

PRMT5 inhibition disrupts splicing and stemness in glioblastoma.

PRMT5 inhibition disrupts splicing and stemness in glioblastoma.

Journal: Nature communications
Published: July 22, 2019

Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor.

Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor.

Journal: Cell reports
Published: June 18, 2019

Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt.

Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt.

Journal: The Journal of clinical investigation
Published: April 05, 2019

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.

Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.

Journal: Genes & development
Published: October 22, 2018

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Journal: Cell stem cell
Published: September 09, 2017

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.

Journal: Cell stem cell
Published: January 05, 2017

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.

Journal: Nature
Published: December 08, 2016

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.

Journal: Cancer cell
Published: June 04, 2015

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.

Journal: Cancer cell
Published: October 31, 2014
Showing 1-12 of 14

Last Updated: 09/26/2026