Last Updated: 09/26/2026
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Found 25 publications
Population Pharmacokinetic Analysis of Vixarelimab in Healthy Volunteers and Patients With Chronic Pruritic Conditions.
Journal: CPT: pharmacometrics & systems pharmacology
Published: November 21, 2025
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Fenebrutinib and Effect on the QT/QTc Interval in Healthy Participants.
Journal: Clinical and translational science
Published: November 12, 2025
Beyond single-dose human mass balance study: minimizing subject confinement and enabling true steady-state assessment with a novel multiple-dose design proposal.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: July 28, 2025
Midbrain extracellular matrix and microglia are associated with cognition in aging mice.
Journal: Nature communications
Published: November 13, 2024
A Phase 1a Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7303509, an Anti-TGFβ3 Antibody, in Healthy Volunteers.
Journal: Rheumatology and therapy
Published: February 02, 2024
Comparative Pharmacokinetics and Safety Assessment of 1st- and 2nd-Generation Zinpentraxin Alfa Drug Products in Healthy Volunteers: A Randomized Crossover Study.
Journal: Clinical pharmacology in drug development
Published: October 31, 2023
Idiopathic pulmonary fibrosis therapy development: a clinical pharmacology perspective.
Journal: Therapeutic advances in respiratory disease
Published: July 01, 2023
A phase I, randomized, ascending-dose study to assess safety, pharmacokinetics, and activity of GDC-8264, a RIP1 inhibitor, in healthy volunteers.
Journal: Clinical and translational science
Published: June 16, 2023
Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases.
Journal: Journal of pharmaceutical sciences
Published: May 11, 2023
Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model.
Journal: Nature communications
Published: October 25, 2021
Last Updated: 09/26/2026