Linda M. Van Der Graaf
Leiden, ZH, Netherlands
Last Updated: 09/26/2026
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Found 26 publications
Loss of astrocytic markers and impaired metabolic function in spinocerebellar ataxia type 7 patient-derived neural cultures.
Journal: Neurobiology of disease
Published: April 24, 2026
Generation of 4 human induced pluripotent stem cell lines (LUMCi070-A, -B, -C, and -D) from a patient with ischemic cerebral small vessel disease.
Journal: Stem cell research
Published: February 19, 2026
Impedance-based phenotypic profiling of metabotropic glutamate receptor ligand responses in SCA1 human iPSC-derived neuronal cultures.
Journal: Neurobiology of disease
Published: December 17, 2025
Generation of an isogenic human induced pluripotent stem cell line for spinocerebellar ataxia type 1.
Journal: Stem cell research
Published: December 12, 2025
Determining off-target effects of splice-switching antisense oligonucleotides using short read RNAseq in neuronally differentiated human induced pluripotent stem cells.
Journal: Human molecular genetics
Published: July 02, 2025
Calcium-Enhanced Medium-Based Delivery of Splice Modulating Antisense Oligonucleotides in 2D and 3D hiPSC-Derived Neuronal Models.
Journal: Biomedicines
Published: July 08, 2024
Generation of human induced pluripotent stem cell lines (LUMCi051-A,B and LUMCi052-A,B,C) of two patients with Spinocerebellar ataxia type 7.
Journal: Stem cell research
Published: April 17, 2024
Spinocerebellar Ataxia Type 1 Characteristics in Patient-Derived Fibroblast and iPSC-Derived Neuronal Cultures.
Journal: Movement disorders : official journal of the Movement Disorder Society
Published: January 12, 2023
Amyloid beta accumulations and enhanced neuronal differentiation in cerebral organoids of Dutch-type cerebral amyloid angiopathy patients.
Journal: Frontiers in aging neuroscience
Published: September 19, 2022
Antisense Oligonucleotide-Induced Amyloid Precursor Protein Splicing Modulation as a Therapeutic Approach for Dutch-Type Cerebral Amyloid Angiopathy.
Journal: Nucleic acid therapeutics
Published: June 01, 2021
Generation of 5 induced pluripotent stem cell lines, LUMCi007-A and B and LUMCi008-A, B and C, from 2 patients with Huntington disease.
Journal: Stem cell research
Published: May 13, 2019
Generation of 3 human induced pluripotent stem cell lines LUMCi005-A, B and C from a Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch type patient.
Journal: Stem cell research
Published: November 01, 2018
Last Updated: 09/26/2026