Linda Z. Penn

Toronto, ON, Canada

Last Updated: 09/26/2026

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Found 66 publications

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.

Journal: Cell reports

Published: June 17, 2026

Association of Cumulative Proton Pump Inhibitor Use with Prostate Cancer Risk and Outcomes: A Population-Based Cohort Study.

Association of Cumulative Proton Pump Inhibitor Use with Prostate Cancer Risk and Outcomes: A Population-Based Cohort Study.

Journal: Cancer research communications

Published: April 03, 2026

Structure and function of the L-MYC N-terminus impacts strategies to inhibit the MYC family of oncoproteins.

Structure and function of the L-MYC N-terminus impacts strategies to inhibit the MYC family of oncoproteins.

Journal: The Biochemical journal

Published: January 23, 2026

Statin use and outcomes in advanced prostate cancer:Secondary analysis of the SPARTAN trial.

Statin use and outcomes in advanced prostate cancer:Secondary analysis of the SPARTAN trial.

Journal: Urologic oncology

Published: November 02, 2025

CHD1 is a synthetic lethal vulnerability in MYC-driven breast cancer.

CHD1 is a synthetic lethal vulnerability in MYC-driven breast cancer.

Journal: Oncogene

Published: July 31, 2025

The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.

The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.

Journal: Nature communications

Published: March 20, 2025

MYC serine 62 phosphorylation promotes its association with DNA double-strand breaks to facilitate repair and cell survival under genotoxic stress.

MYC serine 62 phosphorylation promotes its association with DNA double-strand breaks to facilitate repair and cell survival under genotoxic stress.

Journal: Genes & development

Published: March 19, 2025

Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.

Serine phosphorylation facilitates protein degradation by the human mitochondrial ClpXP protease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 29, 2025

Structural basis of TMPRSS11D specificity and autocleavage activation.

Structural basis of TMPRSS11D specificity and autocleavage activation.

Journal: Nature communications

Published: October 30, 2024

Statin use and oncological outcomes in a propensity-matched cohort of nonmetastatic castration resistant prostate cancer patients of the ARAMIS trial.

Statin use and oncological outcomes in a propensity-matched cohort of nonmetastatic castration resistant prostate cancer patients of the ARAMIS trial.

Journal: Urologic oncology

Published: May 28, 2024

Statin Concentration in Prostatic Tissue is Subtype- and Dose-dependent.

Statin Concentration in Prostatic Tissue is Subtype- and Dose-dependent.

Journal: Urology

Published: March 12, 2024

Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation.

Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 26, 2024

Showing 1-12 of 66

Last Updated: 09/26/2026