Linyuan Peng

State Key Laboratory Of Natural Medicines
Nanjing, 211198, China

Last Updated: 09/26/2026

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Found 10 publications

Reactivation of MAPK-SOX2 pathway confers ferroptosis sensitivity in KRASG12C inhibitor resistant tumors.

Reactivation of MAPK-SOX2 pathway confers ferroptosis sensitivity in KRASG12C inhibitor resistant tumors.

Journal: Redox biology
Published: September 26, 2024

CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism.

CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism.

Journal: Cell reports
Published: April 26, 2024

The hepatic clock synergizes with HIF-1α to regulate nucleotide availability during liver damage repair.

The hepatic clock synergizes with HIF-1α to regulate nucleotide availability during liver damage repair.

Journal: Nature metabolism
Published: December 16, 2023

Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.

Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity.

Journal: Cell reports
Published: September 23, 2023

A Glb1-2A-mCherry reporter monitors systemic aging and predicts lifespan in middle-aged mice.

A Glb1-2A-mCherry reporter monitors systemic aging and predicts lifespan in middle-aged mice.

Journal: Nature communications
Published: April 05, 2021

Lamin A safeguards the m6 A methylase METTL14 nuclear speckle reservoir to prevent cellular senescence.

Lamin A safeguards the m6 A methylase METTL14 nuclear speckle reservoir to prevent cellular senescence.

Journal: Aging cell
Published: February 09, 2020

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice.

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice.

Journal: eLife
Published: February 06, 2020

Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis.

Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis.

Journal: Nucleic acids research
Published: November 28, 2019

PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome.

PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson-Gilford progeria syndrome.

Journal: Aging cell
Published: September 10, 2019

Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.

Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria.

Journal: eLife
Published: January 05, 2018
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Last Updated: 09/26/2026