Lisa M. Ott De Bruin

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 19 publications

RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.

RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.

Journal: Blood advances

Published: April 25, 2025

Safety and efficacy of gene therapy for RAG1-deficient SCID.

Safety and efficacy of gene therapy for RAG1-deficient SCID.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: January 22, 2025

Immunopathological and microbial signatures of inflammatory bowel disease in partial RAG deficiency.

Immunopathological and microbial signatures of inflammatory bowel disease in partial RAG deficiency.

Journal: The Journal of experimental medicine

Published: October 26, 2024

Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs.

Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs.

Journal: Immunology letters

Published: July 23, 2024

Advances in gene therapy for inborn errors of immunity.

Advances in gene therapy for inborn errors of immunity.

Journal: Current opinion in allergy and clinical immunology

Published: October 17, 2023

Persistent Hypogammaglobulinemia after Receiving Rituximab Post-HSCT Is Not Caused by an Intrinsic B Cell Defect.

Persistent Hypogammaglobulinemia after Receiving Rituximab Post-HSCT Is Not Caused by an Intrinsic B Cell Defect.

Journal: International journal of molecular sciences

Published: October 13, 2023

Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations.

Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations.

Journal: Frontiers in immunology

Published: July 28, 2023

Perinatal Infections With Ureaplasma.

Perinatal Infections With Ureaplasma.

Journal: The Pediatric infectious disease journal

Published: May 27, 2021

Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation.

Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation.

Journal: JCI insight

Published: April 27, 2021

Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices.

Cysteine and hydrophobic residues in CDR3 serve as distinct T-cell self-reactivity indices.

Journal: The Journal of allergy and clinical immunology

Published: February 26, 2019

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development.

Hypomorphic Rag1 mutations alter the preimmune repertoire at early stages of lymphoid development.

Journal: Blood

Published: December 09, 2017

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Journal: Frontiers in immunology

Published: September 10, 2017

Showing 1-12 of 19

Last Updated: 09/26/2026