Lixue Chen

No. 9 West Section Lvshun South Road
Dalian, 116044, China

Last Updated: 09/26/2026

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Found 9 publications

Design and Synthesis of KRASG12C Inhibitors for Antitumor Evaluation Harboring Combination Therapy with Nrf2, PARP-7, and Pan-USP Inhibitors to Alleviate Drug Resistance Synergistically.

Design and Synthesis of KRASG12C Inhibitors for Antitumor Evaluation Harboring Combination Therapy with Nrf2, PARP-7, and Pan-USP Inhibitors to Alleviate Drug Resistance Synergistically.

Journal: Journal of medicinal chemistry
Published: February 03, 2026

An injectable dihydroartemisinin nanocomposite hydrogel for dual-targeting PANoptosis and inflammation to treat osteoarthritis.

An injectable dihydroartemisinin nanocomposite hydrogel for dual-targeting PANoptosis and inflammation to treat osteoarthritis.

Journal: Journal of nanobiotechnology
Published: October 16, 2025

Bio-Active Peptides from Marine Sources: Mechanistic Insights into Immune Regulation, Microbiota Modulation, and Intestinal Barrier Protection.

Bio-Active Peptides from Marine Sources: Mechanistic Insights into Immune Regulation, Microbiota Modulation, and Intestinal Barrier Protection.

Journal: International journal of molecular sciences
Published: September 15, 2025

Prodrug-loaded micelles targeting articular cavity reactive oxygen species for rheumatoid arthritis treatment.

Prodrug-loaded micelles targeting articular cavity reactive oxygen species for rheumatoid arthritis treatment.

Journal: Materials today. Bio
Published: September 11, 2025

Pyrimidine compounds BY4003 and BY4008 inhibit glioblastoma cells growth via modulating JAK3/STAT3 signaling pathway.

Pyrimidine compounds BY4003 and BY4008 inhibit glioblastoma cells growth via modulating JAK3/STAT3 signaling pathway.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Published: February 05, 2024

Intelligent triggering of nanomicelles based on a ROS-activated anticancer prodrug and photodynamic therapy (PDT)-synergistic therapy for lung cancers.

Intelligent triggering of nanomicelles based on a ROS-activated anticancer prodrug and photodynamic therapy (PDT)-synergistic therapy for lung cancers.

Journal: European journal of medicinal chemistry
Published: May 11, 2022

Ratiometric co-delivery of doxorubicin and paclitaxel prodrug by remote-loading liposomes for the treatment of triple-negative breast cancer.

Ratiometric co-delivery of doxorubicin and paclitaxel prodrug by remote-loading liposomes for the treatment of triple-negative breast cancer.

Journal: Drug delivery and translational research
Published: December 06, 2021

Novel Potent EGFR-JAK3 Dual-Target Inhibitor that Overcomes KRAS Mutation Resistance in Colorectal Cancer.

Novel Potent EGFR-JAK3 Dual-Target Inhibitor that Overcomes KRAS Mutation Resistance in Colorectal Cancer.

Journal: Anti-cancer agents in medicinal chemistry
Published: November 06, 2021

Honokiol Prodrug Nanoparticles Based on In Situ Albumin Binding for Long Circulation and High Tumor Uptake.

Honokiol Prodrug Nanoparticles Based on In Situ Albumin Binding for Long Circulation and High Tumor Uptake.

Journal: ACS medicinal chemistry letters
Published: August 05, 2021
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Last Updated: 09/26/2026