Liz O'donovan

Francis Crick Avenue
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 12 publications

Modulation of Pro-Inflammatory IL-6 Trans-Signaling Axis by Splice Switching Oligonucleotides as a Therapeutic Modality in Inflammation.

Modulation of Pro-Inflammatory IL-6 Trans-Signaling Axis by Splice Switching Oligonucleotides as a Therapeutic Modality in Inflammation.

Journal: Cells
Published: July 31, 2023

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Journal: Human molecular genetics
Published: July 26, 2018

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.

Journal: PloS one
Published: January 31, 2018

Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD.

Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD.

Journal: Molecular therapy. Nucleic acids
Published: December 18, 2017

In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy.

In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy.

Journal: Methods in molecular biology (Clifton, N.J.)
Published: July 24, 2015

Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides.

Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides.

Journal: Nucleic acid therapeutics
Published: July 16, 2015

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides.

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides.

Journal: Nano letters
Published: June 05, 2015

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse.

Journal: Human molecular genetics
Published: January 26, 2015

Delivery of therapeutic oligonucleotides with cell penetrating peptides.

Delivery of therapeutic oligonucleotides with cell penetrating peptides.

Journal: Advanced drug delivery reviews
Published: January 06, 2015

Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy.

Parallel synthesis of cell-penetrating peptide conjugates of PMO toward exon skipping enhancement in Duchenne muscular dystrophy.

Journal: Nucleic acid therapeutics
Published: November 21, 2014

A hydrazide-anchored dendron scaffold for chemoselective ligation strategies.

A hydrazide-anchored dendron scaffold for chemoselective ligation strategies.

Journal: Organic & biomolecular chemistry
Published: August 12, 2014

A chemical view of oligonucleotides for exon skipping and related drug applications.

A chemical view of oligonucleotides for exon skipping and related drug applications.

Journal: Nucleic acid therapeutics
Published: November 01, 2013
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Last Updated: 09/26/2026