Last Updated: 09/26/2026
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Found 19 publications
Control of tissue oxygenation by S-nitrosohemoglobin in human subjects.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 22, 2023
Synergistic Strategies to Accelerate the Development of Function-Promoting Therapies: Lessons From Operation Warp Speed and Oncology Drug Development.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences
Published: November 28, 2022
Challenges and Future Prospects of Targeting Myostatin/Activin A Signaling to Treat Diseases of Muscle Loss and Metabolic Dysfunction.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences
Published: November 13, 2022
Farnesoid X receptor agonist tropifexor attenuates cholestasis in a randomised trial in patients with primary biliary cholangitis.
Journal: JHEP reports : innovation in hepatology
Published: July 05, 2022
A Study to Evaluate Relative Bioavailability, Food Effect, and Pharmacodynamics of Tropifexor, a Farnesoid X Receptor Agonist, in Healthy Participants.
Journal: Clinical pharmacology in drug development
Published: May 31, 2022
Urinary Monocyte Chemoattractant Protein-1 in Patients With Alport Syndrome.
Journal: Kidney international reports
Published: November 08, 2021
Targeting the biology of ageing with mTOR inhibitors to improve immune function in older adults: phase 2b and phase 3 randomised trials.
Journal: The lancet. Healthy longevity
Published: May 12, 2021
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Non-Bile Acid FXR Agonist Tropifexor (LJN452) in Healthy Volunteers.
Journal: Clinical pharmacology in drug development
Published: April 24, 2019
Tropifexor-Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents.
Journal: Hepatology communications
Published: November 13, 2018
Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences
Published: December 14, 2017
Last Updated: 09/26/2026