Longlong Zhang

Shanghai, 200031, China

Last Updated: 09/26/2026

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Found 15 publications

Science breaks silence.

Science breaks silence.

Journal: Med (New York, N.Y.)

Published: February 09, 2026

Multicentre gene therapy for OTOF-related deafness followed up to 2.5 years.

Multicentre gene therapy for OTOF-related deafness followed up to 2.5 years.

Journal: Nature

Published: September 14, 2025

Re-administration of AAV-mediated gene therapy for OTOF-related deafness: a single-arm trial.

Re-administration of AAV-mediated gene therapy for OTOF-related deafness: a single-arm trial.

Journal: Nature medicine

Published: August 12, 2025

Gene Therapy vs Cochlear Implantation in Restoring Hearing Function and Speech Perception for Individuals With Congenital Deafness.

Gene Therapy vs Cochlear Implantation in Restoring Hearing Function and Speech Perception for Individuals With Congenital Deafness.

Journal: JAMA neurology

Published: July 21, 2025

Comparative analysis of RNA versus protein splicing in dual AAV-mediated gene therapy in a mouse model of DFNB9 deafness.

Comparative analysis of RNA versus protein splicing in dual AAV-mediated gene therapy in a mouse model of DFNB9 deafness.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: March 26, 2025

Audiological characteristics following gene therapy in patients with autosomal recessive deafness 9.

Audiological characteristics following gene therapy in patients with autosomal recessive deafness 9.

Journal: Med (New York, N.Y.)

Published: December 20, 2024

Preliminary evidence for enhanced auditory cortex activation and mental development after gene therapy in children with autosomal recessive deafness 9.

Preliminary evidence for enhanced auditory cortex activation and mental development after gene therapy in children with autosomal recessive deafness 9.

Journal: Nature human behaviour

Published: June 27, 2024

Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results.

Bilateral gene therapy in children with autosomal recessive deafness 9: single-arm trial results.

Journal: Nature medicine

Published: December 15, 2023

AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial.

AAV1-hOTOF gene therapy for autosomal recessive deafness 9: a single-arm trial.

Journal: Lancet (London, England)

Published: November 08, 2023

Engineering of the AAV-Compatible Hair Cell-Specific Small-Size Myo15 Promoter for Gene Therapy in the Inner Ear.

Engineering of the AAV-Compatible Hair Cell-Specific Small-Size Myo15 Promoter for Gene Therapy in the Inner Ear.

Journal: Research (Washington, D.C.)

Published: October 28, 2023

Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model.

Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model.

Journal: Molecular therapy. Nucleic acids

Published: September 18, 2023

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates.

Preclinical evaluation of the efficacy and safety of AAV1-hOTOF in mice and nonhuman primates.

Journal: Molecular therapy. Methods & clinical development

Published: August 25, 2023

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Last Updated: 09/26/2026