Lorenzo L. Casal
Vancouver, BC V5Z4H4, Canada
Last Updated: 09/26/2026
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Found 8 publications
Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease mice.
Journal: Translational neurodegeneration
Published: May 06, 2024
Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: August 13, 2023
Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks.
Journal: Journal of controlled release : official journal of the Controlled Release Society
Published: March 20, 2023
Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Published: July 16, 2020
A Comprehensive Haplotype-Targeting Strategy for Allele-Specific HTT Suppression in Huntington Disease.
Journal: American journal of human genetics
Published: July 15, 2019
Constitutive ablation of caspase-6 reduces the inflammatory response and behavioural changes caused by peripheral pro-inflammatory stimuli.
Journal: Cell death discovery
Published: February 07, 2018
HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo.
Journal: Human molecular genetics
Published: August 22, 2017
Showing 1-8 of 8
Last Updated: 09/26/2026