Lorenzo Manfreda

Via Giustiniani 3
Padova, 35128, Italy

Last Updated: 09/26/2026

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Found 14 publications

NRF2 activation is required for chemotherapy resistance acquisition in medulloblastoma via metabolic and redox adaptation.

NRF2 activation is required for chemotherapy resistance acquisition in medulloblastoma via metabolic and redox adaptation.

Journal: Redox biology

Published: July 29, 2026

Microwave-Enhanced Synthesis of 2-Styrylquinoline-4-Carboxamides With Promising Anti-Lymphoma Activity.

Microwave-Enhanced Synthesis of 2-Styrylquinoline-4-Carboxamides With Promising Anti-Lymphoma Activity.

Journal: Archiv der Pharmazie

Published: July 31, 2025

TrkA activation sustains chemotherapy resistance in chemotolerant medulloblastoma cells.

TrkA activation sustains chemotherapy resistance in chemotolerant medulloblastoma cells.

Journal: Acta neuropathologica communications

Published: June 13, 2025

Connexin hemichannel blockade by abEC1.1 disrupts glioblastoma progression, suppresses invasiveness, and reduces hyperexcitability in preclinical models.

Connexin hemichannel blockade by abEC1.1 disrupts glioblastoma progression, suppresses invasiveness, and reduces hyperexcitability in preclinical models.

Journal: Cell communication and signaling : CCS

Published: April 03, 2025

Design and Synthesis of 2-substituted [1,2,4]Triazolo[1,5-a]pyrimidines Tethered with Umbelliferone as Selective Carbonic Anhydrase IX and XII Inhibitors.

Design and Synthesis of 2-substituted [1,2,4]Triazolo[1,5-a]pyrimidines Tethered with Umbelliferone as Selective Carbonic Anhydrase IX and XII Inhibitors.

Journal: Anti-cancer agents in medicinal chemistry

Published: December 26, 2024

Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold.

Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: October 18, 2023

Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma.

Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma.

Journal: Acta neuropathologica communications

Published: August 03, 2023

Collagen VI sustains cell stemness and chemotherapy resistance in glioblastoma.

Collagen VI sustains cell stemness and chemotherapy resistance in glioblastoma.

Journal: Cellular and molecular life sciences : CMLS

Published: June 04, 2023

Surviving the hunger games: Metabolic reprogramming in medulloblastoma.

Surviving the hunger games: Metabolic reprogramming in medulloblastoma.

Journal: Biochemical pharmacology

Published: May 17, 2023

Wnt Signaling in Brain Tumors: A Challenging Therapeutic Target.

Wnt Signaling in Brain Tumors: A Challenging Therapeutic Target.

Journal: Biology

Published: March 31, 2023

Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.

Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.

Journal: European journal of medicinal chemistry

Published: February 01, 2023

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities.

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: July 28, 2022

Showing 1-12 of 14

Last Updated: 09/26/2026