Lothar Spies

Hamburg, HH 22335, Germany

Last Updated: 09/26/2026

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Found 33 publications

Cognition and fatigue in clinically stable multiple sclerosis: EDSS and MRI metrics outperform serum biomarkers.

Cognition and fatigue in clinically stable multiple sclerosis: EDSS and MRI metrics outperform serum biomarkers.

Journal: BMC neurology

Published: December 05, 2025

Easy-to-use and easy-to-interpret quality control of 3D gradient echo T1-weighted MR acquisition sequences for improved test-retest stability of MRI-based hippocampus volumetry.

Easy-to-use and easy-to-interpret quality control of 3D gradient echo T1-weighted MR acquisition sequences for improved test-retest stability of MRI-based hippocampus volumetry.

Journal: Journal of Alzheimer's disease : JAD

Published: September 24, 2025

Clinical validation of artificial intelligence-based single-subject morphometry without normative reference database.

Clinical validation of artificial intelligence-based single-subject morphometry without normative reference database.

Journal: Journal of Alzheimer's disease : JAD

Published: January 13, 2025

Higher effect sizes for the detection of accelerated brain volume loss and disability progression in multiple sclerosis using deep-learning.

Higher effect sizes for the detection of accelerated brain volume loss and disability progression in multiple sclerosis using deep-learning.

Journal: Computers in biology and medicine

Published: August 21, 2024

An Artificial Intelligence Algorithm Integrated into the Clinical Workflow Can Ensure High Quality Acute Intracranial Hemorrhage CT Diagnostic.

An Artificial Intelligence Algorithm Integrated into the Clinical Workflow Can Ensure High Quality Acute Intracranial Hemorrhage CT Diagnostic.

Journal: Clinical neuroradiology

Published: May 23, 2024

Patients with relapsing-remitting multiple sclerosis show accelerated whole brain volume and thalamic volume loss early in disease.

Patients with relapsing-remitting multiple sclerosis show accelerated whole brain volume and thalamic volume loss early in disease.

Journal: Neuroradiology

Published: January 18, 2024

BrainLossNet: a fast, accurate and robust method to estimate brain volume loss from longitudinal MRI.

BrainLossNet: a fast, accurate and robust method to estimate brain volume loss from longitudinal MRI.

Journal: International journal of computer assisted radiology and surgery

Published: December 20, 2023

Voxel-based morphometry in single subjects without a scanner-specific normal database using a convolutional neural network.

Voxel-based morphometry in single subjects without a scanner-specific normal database using a convolutional neural network.

Journal: European radiology

Published: January 28, 2023

Automatic segmentation of the thalamus using a massively trained 3D convolutional neural network: higher sensitivity for the detection of reduced thalamus volume by improved inter-scanner stability.

Automatic segmentation of the thalamus using a massively trained 3D convolutional neural network: higher sensitivity for the detection of reduced thalamus volume by improved inter-scanner stability.

Journal: European radiology

Published: March 30, 2022

Single-subject analysis of regional brain volumetric measures can be strongly influenced by the method for head size adjustment.

Single-subject analysis of regional brain volumetric measures can be strongly influenced by the method for head size adjustment.

Journal: Neuroradiology

Published: January 18, 2022

Infratentorial lesions in multiple sclerosis patients: intra- and inter-rater variability in comparison to a fully automated segmentation using 3D convolutional neural networks.

Infratentorial lesions in multiple sclerosis patients: intra- and inter-rater variability in comparison to a fully automated segmentation using 3D convolutional neural networks.

Journal: European radiology

Published: June 28, 2021

Age-dependent cut-offs for pathological deep gray matter and thalamic volume loss using Jacobian integration.

Age-dependent cut-offs for pathological deep gray matter and thalamic volume loss using Jacobian integration.

Journal: NeuroImage. Clinical

Published: August 04, 2020

Showing 1-12 of 33

Last Updated: 09/26/2026