Luba Simhaev

Tel Aviv, TA 69978, Israel

Last Updated: 09/26/2026

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Found 16 publications

Targeting phenylalanine assemblies as a prospective disease-modifying therapy for phenylketonuria.

Targeting phenylalanine assemblies as a prospective disease-modifying therapy for phenylketonuria.

Journal: Biophysical chemistry

Published: December 29, 2023

Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment.

Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: August 15, 2022

Exploring the Li+ transporting mutant of NCX_Mj for assigning ion binding sites of mitochondrial NCLX.

Exploring the Li+ transporting mutant of NCX_Mj for assigning ion binding sites of mitochondrial NCLX.

Journal: Cell calcium

Published: July 06, 2022

The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity.

The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity.

Journal: International journal of biological macromolecules

Published: October 25, 2021

Chemical Chaperones Modulate the Formation of Metabolite Assemblies.

Chemical Chaperones Modulate the Formation of Metabolite Assemblies.

Journal: International journal of molecular sciences

Published: August 08, 2021

The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue.

The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue.

Journal: The Journal of biological chemistry

Published: January 21, 2021

TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8AKT1/SGK1 define separate branches of the stress response mechanisms in fission yeast.

TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8AKT1/SGK1 define separate branches of the stress response mechanisms in fission yeast.

Journal: PLoS genetics

Published: July 24, 2020

A unique mechanism of inactivation gating of the Kv channel family member Kv7.1 and its modulation by PIP2 and calmodulin.

A unique mechanism of inactivation gating of the Kv channel family member Kv7.1 and its modulation by PIP2 and calmodulin.

Journal: Science advances

Published: July 06, 2020

Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex.

Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex.

Journal: Nature communications

Published: June 22, 2020

A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.

A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.

Journal: Scientific reports

Published: September 22, 2019

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.

An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.

Journal: Developmental cell

Published: September 18, 2018

Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-Pα,α-Dithiophosphate Analogues.

Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-Pα,α-Dithiophosphate Analogues.

Journal: Journal of medicinal chemistry

Published: April 24, 2018

Showing 1-12 of 16

Last Updated: 09/26/2026