Luca Broggini
Milan, Italy
Last Updated: 09/26/2026
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Found 16 publications
Exploring light chain cardiotoxicity in AL amyloidosis: impact on hiPSC-derived cardiomyocyte activity.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Published: June 19, 2026
Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 25, 2026
Untwisted amyloid fibrils from a transgenic mouse model of AL amyloidosis.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
Published: December 21, 2025
Multifaceted effects of N-glycosylation on amyloidogenic κ light chains in AL amyloidosis.
Journal: Structure (London, England : 1993)
Published: October 09, 2025
The Critical Role of the Variable Domain in Driving Proteotoxicity and Aggregation in Full-length Light Chains.
Journal: Journal of molecular biology
Published: October 15, 2024
Defective cell-autonomous signalling and antigenic polyreactivity of B-cell receptors from chronic lymphocytic leukaemia stereotyped subset 1.
Journal: Nature communications
Published: October 08, 2024
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent.
Journal: Acta crystallographica. Section D, Structural biology
Published: January 30, 2024
Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation.
Journal: Journal of molecular biology
Published: June 22, 2023
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: June 23, 2022
β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression.
Journal: Immunity
Published: January 20, 2021
Last Updated: 09/26/2026