Luca Gasparoli

UCL Great Ormond Street Institute Of Child Health
London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

MCL1 inhibition to enhance the efficacy of MYB targeting in pediatric acute myeloid leukemia.

MCL1 inhibition to enhance the efficacy of MYB targeting in pediatric acute myeloid leukemia.

Journal: Cell death & disease
Published: August 22, 2025

Retraction Note: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer.

Retraction Note: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer.

Journal: Scientific reports
Published: January 28, 2025

Susceptibility of pediatric acute lymphoblastic leukemia to STAT3 inhibition depends on p53 induction.

Susceptibility of pediatric acute lymphoblastic leukemia to STAT3 inhibition depends on p53 induction.

Journal: Haematologica
Published: May 25, 2023

Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias.

Direct targeted therapy for MLL-fusion-driven high-risk acute leukaemias.

Journal: Clinical and translational medicine
Published: February 15, 2022

Identification of a c-MYB-directed therapeutic for acute myeloid leukemia.

Identification of a c-MYB-directed therapeutic for acute myeloid leukemia.

Journal: Leukemia
Published: November 26, 2021

ARHGEF4 Regulates an Essential Oncogenic Program in t(12;21)-Associated Acute Lymphoblastic Leukemia.

ARHGEF4 Regulates an Essential Oncogenic Program in t(12;21)-Associated Acute Lymphoblastic Leukemia.

Journal: HemaSphere
Published: May 12, 2020

Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.

Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.

Journal: Science translational medicine
Published: May 08, 2019

The AAA+ATPase RUVBL2 is essential for the oncogenic function of c-MYB in acute myeloid leukemia.

The AAA+ATPase RUVBL2 is essential for the oncogenic function of c-MYB in acute myeloid leukemia.

Journal: Leukemia
Published: March 13, 2019

The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.

The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.

Journal: British journal of cancer
Published: July 29, 2017

The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.

The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.

Journal: Science signaling
Published: April 06, 2017

Macrolide antibiotics exert antileukemic effects by modulating the autophagic flux through inhibition of hERG1 potassium channels.

Macrolide antibiotics exert antileukemic effects by modulating the autophagic flux through inhibition of hERG1 potassium channels.

Journal: Blood cancer journal
Published: May 14, 2016

New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.

New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.

Journal: Molecular pharmacology
Published: November 21, 2014
Showing 1-12 of 16

Last Updated: 09/26/2026