Luca Orlando

Hamilton, ON, Canada

Last Updated: 09/26/2026

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Found 16 publications

Chemical genomics reveals targetable programs of human cancers rooted in pluripotency.

Chemical genomics reveals targetable programs of human cancers rooted in pluripotency.

Journal: Cell chemical biology

Published: December 06, 2022

Evidence-based support for phenotypic drug discovery in acute myeloid leukemia.

Evidence-based support for phenotypic drug discovery in acute myeloid leukemia.

Journal: Drug discovery today

Published: June 11, 2022

Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.

Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.

Journal: Cell chemical biology

Published: November 01, 2020

Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients.

Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients.

Journal: Cell reports

Published: June 11, 2020

Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells.

Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells.

Journal: Cell

Published: September 29, 2018

Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.

Induced Pluripotent Stem Cells: Advances in the Quest for Genetic Stability during Reprogramming Process.

Journal: International journal of molecular sciences

Published: July 21, 2017

Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions.

Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions.

Journal: Cell reports

Published: May 26, 2017

Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations.

Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations.

Journal: Stem cells (Dayton, Ohio)

Published: February 28, 2017

Sam68 Allows Selective Targeting of Human Cancer Stem Cells.

Sam68 Allows Selective Targeting of Human Cancer Stem Cells.

Journal: Cell chemical biology

Published: February 01, 2017

Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media.

Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media.

Journal: Stem cell research

Published: June 12, 2015

Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts.

Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts.

Journal: Stem cell research

Published: December 10, 2014

Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease.

Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease.

Journal: International journal of molecular sciences

Published: November 13, 2012

Showing 1-12 of 16

Last Updated: 09/26/2026