Luca Varani

Bellinzona, TI 6500, Switzerland

Last Updated: 09/26/2026

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Found 64 publications

Rationally Modified SARS-CoV-2 Spike Protein Impairs ACE2 Binding While Preserving Immunogenicity in Mice.

Rationally Modified SARS-CoV-2 Spike Protein Impairs ACE2 Binding While Preserving Immunogenicity in Mice.

Journal: Vaccines

Published: June 01, 2026

Human antibodies against West Nile and related orthoflaviviruses.

Human antibodies against West Nile and related orthoflaviviruses.

Journal: bioRxiv : the preprint server for biology

Published: April 17, 2026

Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses.

Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses.

Journal: Immunity

Published: August 18, 2025

Mapping Antibody Epitopes by Solution NMR Spectroscopy: Practical Considerations.

Mapping Antibody Epitopes by Solution NMR Spectroscopy: Practical Considerations.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: July 02, 2025

Regulatory factor X 7 limits Myc activity during B cell activation and suppresses Myc-dependent lymphomagenesis.

Regulatory factor X 7 limits Myc activity during B cell activation and suppresses Myc-dependent lymphomagenesis.

Journal: Nature immunology

Published: March 07, 2025

Ultrapotent IgA dimeric antibodies neutralize emerging Omicron variants.

Ultrapotent IgA dimeric antibodies neutralize emerging Omicron variants.

Journal: Journal of virology

Published: December 04, 2024

Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches.

Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches.

Journal: Emerging microbes & infections

Published: November 25, 2024

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages.

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 09, 2024

Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses.

Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses.

Journal: Cell reports

Published: November 09, 2023

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer.

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer.

Journal: International journal of molecular sciences

Published: August 15, 2023

Adapting Neutralizing Antibodies to Viral Variants by Structure-Guided Affinity Maturation Using Phage Display Technology.

Adapting Neutralizing Antibodies to Viral Variants by Structure-Guided Affinity Maturation Using Phage Display Technology.

Journal: Global challenges (Hoboken, NJ)

Published: May 26, 2023

Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein.

Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein.

Journal: Science immunology

Published: January 26, 2023

Showing 1-12 of 64

Last Updated: 09/26/2026