Lucas Chan

London, ENG SE59NT, United Kingdom

Last Updated: 09/26/2026

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Found 11 publications

Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Ex Vivo Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA.

Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Ex Vivo Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA.

Journal: Molecular therapy. Methods & clinical development

Published: January 14, 2019

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa.

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa.

Journal: JCI insight

Published: December 05, 2018

Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell.

Lentiviral Vector Purification Using Genetically Encoded Biotin Mimic in Packaging Cell.

Journal: Molecular therapy. Methods & clinical development

Published: April 12, 2018

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.

Journal: Science translational medicine

Published: July 08, 2016

Transient Expression of Green Fluorescent Protein in Integrase-Defective Lentiviral Vector-Transduced 293T Cell Line.

Transient Expression of Green Fluorescent Protein in Integrase-Defective Lentiviral Vector-Transduced 293T Cell Line.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: June 19, 2016

ASH1L (a histone methyltransferase protein) is a novel candidate globin gene regulator revealed by genetic study of an English family with beta-thalassaemia unlinked to the beta-globin locus.

ASH1L (a histone methyltransferase protein) is a novel candidate globin gene regulator revealed by genetic study of an English family with beta-thalassaemia unlinked to the beta-globin locus.

Journal: British journal of haematology

Published: February 05, 2016

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

Journal: The Journal of investigative dermatology

Published: May 07, 2015

Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient.

Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient.

Journal: Journal of hepatology

Published: June 04, 2014

Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome.

Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome.

Journal: Human gene therapy. Clinical development

Published: December 17, 2013

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene.

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene.

Journal: PloS one

Published: May 13, 2013

Efficacy and safety of deferasirox at low and high iron burdens: results from the EPIC magnetic resonance imaging substudy.

Efficacy and safety of deferasirox at low and high iron burdens: results from the EPIC magnetic resonance imaging substudy.

Journal: Annals of hematology

Published: September 20, 2012

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Last Updated: 09/26/2026