Lucas Kissling
Zurich, ZH, Switzerland
Last Updated: 09/26/2026
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Found 19 publications
Prime editing of a pathogenic Scn1a allele ameliorates seizure phenotypes in a GEFS+ mouse model.
Journal: Science translational medicine
Published: May 13, 2026
RNA-LNP-mediated in vivo prime editing corrects disease phenotypes in a mouse model of citrullinemia type I.
Journal: Science translational medicine
Published: May 13, 2026
Prime editing of the β1 adrenoceptor in the brain restores physiological REM sleep in a mouse model of Alzheimer's disease.
Journal: Nature communications
Published: March 05, 2025
BindCraft: one-shot design of functional protein binders.
Journal: bioRxiv : the preprint server for biology
Published: December 16, 2024
One-shot design of functional protein binders with BindCraft.
Journal: Nature
Published: December 07, 2024
Spatial profiling of gene editing by in situ sequencing in mice and macaques.
Journal: Nature biomedical engineering
Published: August 20, 2024
Predicting adenine base editing efficiencies in different cellular contexts by deep learning.
Journal: Genome biology
Published: August 01, 2024
Enhancing prime editor activity by directed protein evolution in yeast.
Journal: Nature communications
Published: November 17, 2023
In vivo base editing of a pathogenic Eif2b5 variant improves vanishing white matter phenotypes in mice.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: October 17, 2023
Machine learning prediction of prime editing efficiency across diverse chromatin contexts.
Journal: Nature biotechnology
Published: October 08, 2023
Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs.
Journal: Nature methods
Published: October 04, 2023
Last Updated: 09/26/2026