Lucca M. Derks

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 11 publications

Single-cell whole-genome sequencing reveals convergent evolution in Burkitt lymphoma.

Single-cell whole-genome sequencing reveals convergent evolution in Burkitt lymphoma.

Journal: Nature communications
Published: November 26, 2025

UV-induced mutations accumulate during early clonal expansion in aneuploid subtypes of pediatric B-cell precursor acute lymphoblastic leukemia.

UV-induced mutations accumulate during early clonal expansion in aneuploid subtypes of pediatric B-cell precursor acute lymphoblastic leukemia.

Journal: Haematologica
Published: October 29, 2025

Posttransplantation clonal dynamics of hematopoietic stem cells carrying prenatal and early-life DNMT3A mutations.

Posttransplantation clonal dynamics of hematopoietic stem cells carrying prenatal and early-life DNMT3A mutations.

Journal: HemaSphere
Published: June 25, 2025

High-resolution single-cell mapping of clonal hematopoiesis and structural variation in aplastic anemia.

High-resolution single-cell mapping of clonal hematopoiesis and structural variation in aplastic anemia.

Journal: Nature genetics
Published: October 25, 2024

Protocol for genome-wide analysis of somatic variants at single-cell resolution using primary template-directed DNA amplification.

Protocol for genome-wide analysis of somatic variants at single-cell resolution using primary template-directed DNA amplification.

Journal: STAR protocols
Published: September 13, 2024

Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools.

Protocol to create isogenic disease models from adult stem cell-derived organoids using next-generation CRISPR tools.

Journal: STAR protocols
Published: March 29, 2024

Stem cell mutations, associated cancer risk, and consequences for regenerative medicine.

Stem cell mutations, associated cancer risk, and consequences for regenerative medicine.

Journal: Cell stem cell
Published: July 17, 2023

Selective pressures of platinum compounds shape the evolution of therapy-related myeloid neoplasms.

Selective pressures of platinum compounds shape the evolution of therapy-related myeloid neoplasms.

Journal: Nature communications
Published: June 12, 2023

Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox.

Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox.

Journal: Cell genomics
Published: February 01, 2023

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids.

One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids.

Journal: Nature communications
Published: May 17, 2022

Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage.

Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage.

Journal: PLoS biology
Published: May 10, 2021
Showing 1-11 of 11

Last Updated: 09/26/2026