Lucien A. Aarden
Amsterdam, NH, Netherlands
Last Updated: 09/26/2026
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Found 15 publications
Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions.
Journal: Frontiers in immunology
Published: April 27, 2017
FSAP-mediated nucleosome release from late apoptotic cells is inhibited by autoantibodies present in SLE.
Journal: European journal of immunology
Published: August 17, 2015
Response to: 'The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region' by Rinaudo-Gaujous et al.
Journal: Annals of the rheumatic diseases
Published: March 16, 2015
An improved monocyte activation test using cryopreserved pooled human mononuclear cells.
Journal: Innate immunity
Published: December 08, 2014
The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.
Journal: Annals of the rheumatic diseases
Published: October 25, 2014
Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.
Journal: The Journal of biological chemistry
Published: October 19, 2014
Key findings towards optimising adalimumab treatment: the concentration-effect curve.
Journal: Annals of the rheumatic diseases
Published: December 12, 2013
Cooperation of factor VII-activating protease and serum DNase I in the release of nucleosomes from necrotic cells.
Journal: Arthritis & rheumatology (Hoboken, N.J.)
Published: June 24, 2013
The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab.
Journal: Journal of immunotoxicology
Published: June 07, 2013
A preliminary algorithm introducing immunogenicity assessment in the management of patients with RA receiving tumour necrosis factor inhibitor therapies.
Journal: Annals of the rheumatic diseases
Published: May 14, 2013
Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation.
Journal: Annals of the rheumatic diseases
Published: January 10, 2013
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
Journal: Annals of the rheumatic diseases
Published: July 05, 2012
Last Updated: 09/26/2026