Lucy A. Waskell

Anesthesiology

1500 E Medical Center Dr Spc 5048
Ann Arbor, MI 48109

Last Updated: 09/26/2026

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Found 38 publications

Similar Rates of Second Electron Transfer and Single-Turnover Dehydroepiandrosterone Formation for Oxyferrous Human Cytochrome P450 17A1 (Steroid 17-Hydroxylase/17,20-lyase)-17-hydroxypregnenolone Complex with Either Human Cytochrome P450-Oxidoreductase or Human Cytochrome b5.

Similar Rates of Second Electron Transfer and Single-Turnover Dehydroepiandrosterone Formation for Oxyferrous Human Cytochrome P450 17A1 (Steroid 17-Hydroxylase/17,20-lyase)-17-hydroxypregnenolone Complex with Either Human Cytochrome P450-Oxidoreductase or Human Cytochrome b5.

Journal: Biochemistry

Published: May 09, 2025

A flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity.

A flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity.

Journal: Journal of inorganic biochemistry

Published: April 02, 2024

The FMN "140s Loop" of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450.

The FMN "140s Loop" of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450.

Journal: International journal of molecular sciences

Published: August 31, 2021

Expression, purification, and functional reconstitution of 19F-labeled cytochrome b5 in peptide nanodiscs for NMR studies.

Expression, purification, and functional reconstitution of 19F-labeled cytochrome b5 in peptide nanodiscs for NMR studies.

Journal: Biochimica et biophysica acta. Biomembranes

Published: November 15, 2019

Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs.

Effect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs.

Journal: Chemical communications (Cambridge, England)

Published: August 11, 2018

Lipid-exchange in nanodiscs discloses membrane boundaries of cytochrome-P450 reductase.

Lipid-exchange in nanodiscs discloses membrane boundaries of cytochrome-P450 reductase.

Journal: Chemical communications (Cambridge, England)

Published: June 05, 2018

Substrate mediated redox partner selectivity of cytochrome P450.

Substrate mediated redox partner selectivity of cytochrome P450.

Journal: Chemical communications (Cambridge, England)

Published: May 22, 2018

A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs.

A Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs.

Journal: Angewandte Chemie (International ed. in English)

Published: February 19, 2018

Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.

Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.

Journal: Biochemistry

Published: January 09, 2018

Cytochrome-P450-Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs.

Cytochrome-P450-Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs.

Journal: Angewandte Chemie (International ed. in English)

Published: December 27, 2017

Structure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam.

Structure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam.

Journal: Journal of inorganic biochemistry

Published: December 20, 2017

Membrane environment drives cytochrome P450's spin transition and its interaction with cytochrome b5.

Membrane environment drives cytochrome P450's spin transition and its interaction with cytochrome b5.

Journal: Chemical communications (Cambridge, England)

Published: November 17, 2017

Showing 1-12 of 38

Last Updated: 09/26/2026