Lucy C. Young

Early Oncology R&D
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 39 publications

NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions.

NF1 and SPRED1/2 cooperate through RAS-MAPK-independent functions.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: May 27, 2026

Engineered Caf1 Constructs Encoding Laminin-332 Motifs: A Novel Approach for Enhanced Cutaneous Wound Healing.

Engineered Caf1 Constructs Encoding Laminin-332 Motifs: A Novel Approach for Enhanced Cutaneous Wound Healing.

Journal: The British journal of dermatology

Published: October 05, 2025

Modulation of the 14-3-3σ/C-RAF "auto"inhibited complex by molecular glues.

Modulation of the 14-3-3σ/C-RAF "auto"inhibited complex by molecular glues.

Journal: bioRxiv : the preprint server for biology

Published: August 06, 2025

Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.

Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.

Journal: Science (New York, N.Y.)

Published: July 24, 2025

BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction.

BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction.

Journal: Science (New York, N.Y.)

Published: June 12, 2025

Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors.

Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors.

Journal: Nature communications

Published: May 05, 2025

KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer.

KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer.

Journal: Cancer cell

Published: August 08, 2024

Study protocol for writing to heal: A culturally based brief expressive writing intervention for Chinese immigrant breast cancer survivors.

Study protocol for writing to heal: A culturally based brief expressive writing intervention for Chinese immigrant breast cancer survivors.

Journal: PloS one

Published: June 18, 2024

The impact of a small-group mammography video discussion on promoting screening uptake among nonadherent Chinese American immigrant women: A randomized controlled trial.

The impact of a small-group mammography video discussion on promoting screening uptake among nonadherent Chinese American immigrant women: A randomized controlled trial.

Journal: Cancer

Published: January 16, 2024

Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization.

Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 23, 2023

Targeting DNA damage response components induces enhanced STING-dependent type-I IFN response in ATM deficient cancer cells and drives dendritic cell activation.

Targeting DNA damage response components induces enhanced STING-dependent type-I IFN response in ATM deficient cancer cells and drives dendritic cell activation.

Journal: Oncoimmunology

Published: September 19, 2022

Past, present, and future of the Living Planet Index.

Past, present, and future of the Living Planet Index.

Journal: npj biodiversity

Published: September 08, 2022

Showing 1-12 of 39

Last Updated: 09/26/2026