Lucy E. Farrimond

Oxford, ENG OX39DU, United Kingdom

Last Updated: 09/26/2026

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Found 12 publications

Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons.

Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons.

Journal: Stem cell reports
Published: August 29, 2023

C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9.

C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9.

Journal: Nature communications
Published: February 09, 2023

Advantages of routine next-generation sequencing over standard genetic testing in the amyotrophic lateral sclerosis clinic.

Advantages of routine next-generation sequencing over standard genetic testing in the amyotrophic lateral sclerosis clinic.

Journal: European journal of neurology
Published: September 12, 2022

Human iPSC co-culture model to investigate the interaction between microglia and motor neurons.

Human iPSC co-culture model to investigate the interaction between microglia and motor neurons.

Journal: Scientific reports
Published: May 15, 2022

A case of SOD1 deficiency: implications for clinical trials.

A case of SOD1 deficiency: implications for clinical trials.

Journal: Brain : a journal of neurology
Published: February 10, 2022

Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain.

Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain.

Journal: Brain communications
Published: November 16, 2021

Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.

Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.

Journal: Stem cell reports
Published: August 04, 2019

Memantine for dementia.

Memantine for dementia.

Journal: The Cochrane database of systematic reviews
Published: March 21, 2019

Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.

Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.

Journal: Neurobiology of disease
Published: May 17, 2018

Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis.

Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis.

Journal: EBioMedicine
Published: May 03, 2018

TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca²⁺ signaling in motor neurons.

TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca²⁺ signaling in motor neurons.

Journal: Neurobiology of disease
Published: March 18, 2014

Memantine and cholinesterase inhibitor combination therapy for Alzheimer's disease: a systematic review.

Memantine and cholinesterase inhibitor combination therapy for Alzheimer's disease: a systematic review.

Journal: BMJ open
Published: June 13, 2012
Showing 1-12 of 12

Last Updated: 09/26/2026