Last Updated: 09/26/2026
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Found 4 publications
Regioselective alkylation of a versatile indazole: Electrophile scope and mechanistic insights from density functional theory calculations.
Journal: Beilstein journal of organic chemistry
Published: March 15, 2024
Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.
Journal: Bioorganic & medicinal chemistry
Published: July 19, 2022
Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon.
Journal: Bioorganic & medicinal chemistry
Published: July 15, 2022
Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE).
Journal: Journal of medicinal chemistry
Published: August 26, 2021
Showing 1-4 of 4
Last Updated: 09/26/2026