Luis A. Lopez-Flores

Avenida De Los Barrios 1, Los Reyes Ixtacala, CP
Tlalnepantla, MEX 54090, Mexico

Last Updated: 09/26/2026

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Found 21 publications

Evaluation of Darifenacin for T-Cell Acute Lymphoblastic Leukemia: Selective Targeting of the Non-Neuronal Cholinergic System and Lysosomal Cathepsins.

Evaluation of Darifenacin for T-Cell Acute Lymphoblastic Leukemia: Selective Targeting of the Non-Neuronal Cholinergic System and Lysosomal Cathepsins.

Journal: International journal of molecular sciences

Published: June 10, 2026

Selective Anti-Giardial Action of Indirubin: Biochemical and Functional Evidence for Inhibition of Triosephosphate Isomerase and Aldose Reductase in Giardia lamblia.

Selective Anti-Giardial Action of Indirubin: Biochemical and Functional Evidence for Inhibition of Triosephosphate Isomerase and Aldose Reductase in Giardia lamblia.

Journal: International journal of molecular sciences

Published: March 28, 2026

Post-translational modifications of triosephosphate isomerase reveal metabolic vulnerabilities in T-ALL: effect of combining dichloroacetic acid and the PPI rabeprazole.

Post-translational modifications of triosephosphate isomerase reveal metabolic vulnerabilities in T-ALL: effect of combining dichloroacetic acid and the PPI rabeprazole.

Journal: The Biochemical journal

Published: September 24, 2025

Targeting G6PD with Benzimidazole and Thiazole Derivatives Suppresses SIRT 2 and VEGF Expression and Induces Cytotoxicity in Glioma Cells.

Targeting G6PD with Benzimidazole and Thiazole Derivatives Suppresses SIRT 2 and VEGF Expression and Induces Cytotoxicity in Glioma Cells.

Journal: International journal of molecular sciences

Published: August 02, 2025

High glucose promotes cisplatin chemoresistance in MDA-MB-231 breast cancer derived cells through changes in gene expression and multiple signaling pathways.

High glucose promotes cisplatin chemoresistance in MDA-MB-231 breast cancer derived cells through changes in gene expression and multiple signaling pathways.

Journal: Biomedical reports

Published: April 04, 2025

In silico design of ankyrin repeat proteins that bind to the insulin-like growth factor type 1 receptor.

In silico design of ankyrin repeat proteins that bind to the insulin-like growth factor type 1 receptor.

Journal: Journal of molecular graphics & modelling

Published: February 11, 2025

Methylglyoxal-Induced Modifications in Human Triosephosphate Isomerase: Structural and Functional Repercussions of Specific Mutations.

Methylglyoxal-Induced Modifications in Human Triosephosphate Isomerase: Structural and Functional Repercussions of Specific Mutations.

Journal: Molecules (Basel, Switzerland)

Published: September 02, 2024

Selective Inhibition of Deamidated Triosephosphate Isomerase by Disulfiram, Curcumin, and Sodium Dichloroacetate: Synergistic Therapeutic Strategies for T-Cell Acute Lymphoblastic Leukemia in Jurkat Cells.

Selective Inhibition of Deamidated Triosephosphate Isomerase by Disulfiram, Curcumin, and Sodium Dichloroacetate: Synergistic Therapeutic Strategies for T-Cell Acute Lymphoblastic Leukemia in Jurkat Cells.

Journal: Biomolecules

Published: August 27, 2024

Pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (Review).

Pancreatic β‑cell apoptosis in type 2 diabetes is related to post‑translational modifications of p53 (Review).

Journal: Molecular medicine reports

Published: April 05, 2024

Preliminary exploration of the expression of acetylcholinesterase in normal human T lymphocytes and leukemic Jurkat T cells.

Preliminary exploration of the expression of acetylcholinesterase in normal human T lymphocytes and leukemic Jurkat T cells.

Journal: Biomedical reports

Published: March 07, 2024

Human Triosephosphate Isomerase Is a Potential Target in Cancer Due to Commonly Occurring Post-Translational Modifications.

Human Triosephosphate Isomerase Is a Potential Target in Cancer Due to Commonly Occurring Post-Translational Modifications.

Journal: Molecules (Basel, Switzerland)

Published: June 14, 2023

The Giardial Arginine Deiminase Participates in Giardia-Host Immunomodulation in a Structure-Dependent Fashion via Toll-like Receptors.

The Giardial Arginine Deiminase Participates in Giardia-Host Immunomodulation in a Structure-Dependent Fashion via Toll-like Receptors.

Journal: International journal of molecular sciences

Published: August 22, 2022

Showing 1-12 of 21

Last Updated: 09/26/2026