Luis C. Morales

Edmonton, AB T6G2R3, Canada

Last Updated: 09/26/2026

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Found 13 publications

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo.

Gangliosides modulate the secretion of extracellular vesicles and their misfolded protein cargo.

Journal: Science advances

Published: September 17, 2025

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease.

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease.

Journal: Pharmaceutics

Published: April 04, 2025

Lipid-Modified PEI Derivative-Based Binary/Ternary Polyplex Formulations for the Delivery of pDNA and mRNA in Primary Cells.

Lipid-Modified PEI Derivative-Based Binary/Ternary Polyplex Formulations for the Delivery of pDNA and mRNA in Primary Cells.

Journal: Biomacromolecules

Published: March 28, 2025

Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model.

Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model.

Journal: Biomolecules

Published: October 22, 2024

Tuning the Potency of Farnesol-Modified Polyethylenimine with Polyanionic Trans-Booster to Enhance DNA Delivery.

Tuning the Potency of Farnesol-Modified Polyethylenimine with Polyanionic Trans-Booster to Enhance DNA Delivery.

Journal: ACS biomaterials science & engineering

Published: February 09, 2024

Biodistribution of Therapeutic Small Interfering RNAs Delivered with Lipid-Substituted Polyethylenimine-Based Delivery Systems.

Biodistribution of Therapeutic Small Interfering RNAs Delivered with Lipid-Substituted Polyethylenimine-Based Delivery Systems.

Journal: Molecular pharmaceutics

Published: January 31, 2024

Lipopolymer mediated siRNA delivery targeting aberrant oncogenes for effective therapy of myeloid leukemia in preclinical animal models.

Lipopolymer mediated siRNA delivery targeting aberrant oncogenes for effective therapy of myeloid leukemia in preclinical animal models.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: November 20, 2023

Transfection Efficacy and Cellular Uptake of Lipid-Modified Polyethyleneimine Derivatives for Anionic Nanoparticles as Gene Delivery Vectors.

Transfection Efficacy and Cellular Uptake of Lipid-Modified Polyethyleneimine Derivatives for Anionic Nanoparticles as Gene Delivery Vectors.

Journal: ACS applied bio materials

Published: February 28, 2023

Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles.

Safe and effective in vivo delivery of DNA and RNA using proteolipid vehicles.

Journal: Cell

Published: September 27, 2022

In-Cell Labeling Coupled to Direct Analysis of Extracellular Vesicles in the Conditioned Medium to Study Extracellular Vesicles Secretion with Minimum Sample Processing and Particle Loss.

In-Cell Labeling Coupled to Direct Analysis of Extracellular Vesicles in the Conditioned Medium to Study Extracellular Vesicles Secretion with Minimum Sample Processing and Particle Loss.

Journal: Cells

Published: December 22, 2021

Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import.

Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import.

Journal: Human molecular genetics

Published: August 12, 2019

Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations.

Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations.

Journal: Nature communications

Published: March 21, 2018

Showing 1-12 of 13

Last Updated: 09/26/2026