Lujun M. Chen

Changzhou, China

Last Updated: 09/26/2026

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Found 105 publications

Colorectal cancer liver metastasis: immunosuppressive microenvironment, signaling pathways, and emerging therapeutic strategies.

Colorectal cancer liver metastasis: immunosuppressive microenvironment, signaling pathways, and emerging therapeutic strategies.

Journal: Frontiers in immunology

Published: April 14, 2026

Mechanistic insights into cordycepin-enhanced CTLA-4 blockade efficacy via Eubacterium rectale-mediated immunomodulation in colon cancer.

Mechanistic insights into cordycepin-enhanced CTLA-4 blockade efficacy via Eubacterium rectale-mediated immunomodulation in colon cancer.

Journal: International immunopharmacology

Published: December 29, 2025

CX3CR1 identifies a potent effector CD8+ T cell subset associated with anti-PD-1 therapeutic efficacy in colorectal cancer.

CX3CR1 identifies a potent effector CD8+ T cell subset associated with anti-PD-1 therapeutic efficacy in colorectal cancer.

Journal: Frontiers in immunology

Published: December 17, 2025

KRT15 drives immunosuppression in esophageal squamous cell carcinoma through GSK3β/β-catenin/CD276 signaling.

KRT15 drives immunosuppression in esophageal squamous cell carcinoma through GSK3β/β-catenin/CD276 signaling.

Journal: Experimental cell research

Published: December 17, 2025

CD8+ TEMRA cells: A double-edged sword in immunity and disease-Mechanisms and therapeutic targets.

CD8+ TEMRA cells: A double-edged sword in immunity and disease-Mechanisms and therapeutic targets.

Journal: International immunopharmacology

Published: December 07, 2025

IL-1β-mediated suppression of CIITA attenuates IFN-γ-induced MHC-II expression on Fibroblasts.

IL-1β-mediated suppression of CIITA attenuates IFN-γ-induced MHC-II expression on Fibroblasts.

Journal: Cell communication and signaling : CCS

Published: September 11, 2025

NK cells limit the synergistic anti-tumor effect of PD-1 inhibition and βγ-biased IL-2.

NK cells limit the synergistic anti-tumor effect of PD-1 inhibition and βγ-biased IL-2.

Journal: International journal of biological macromolecules

Published: July 25, 2025

Tissue-resident Limosilactobacillus reuteri modulates intratumoral arachidonic acid metabolism to enhance CD8+ T cell-mediated anti-PD1 response.

Tissue-resident Limosilactobacillus reuteri modulates intratumoral arachidonic acid metabolism to enhance CD8+ T cell-mediated anti-PD1 response.

Journal: Journal of translational medicine

Published: July 22, 2025

Progenitor-exhausted T cell as prognostic indicator in esophageal squamous cell carcinoma: illuminating their key contribution to tumor immunity.

Progenitor-exhausted T cell as prognostic indicator in esophageal squamous cell carcinoma: illuminating their key contribution to tumor immunity.

Journal: Frontiers in immunology

Published: July 03, 2025

IL-1R2 promotes tumorigenesis and modulates the tumor immune microenvironment in colorectal cancer.

IL-1R2 promotes tumorigenesis and modulates the tumor immune microenvironment in colorectal cancer.

Journal: Cancer immunology, immunotherapy : CII

Published: May 29, 2025

A Comprehensive Review of AIM2 in Cancer: Functional Roles, Molecular Pathways, and Clinical Relevance.

A Comprehensive Review of AIM2 in Cancer: Functional Roles, Molecular Pathways, and Clinical Relevance.

Journal: Journal of immunology research

Published: May 09, 2025

Novel VSMC-associated biomarkers in intracranial aneurysm pathogenesis: a multi-omics and machine learning study.

Novel VSMC-associated biomarkers in intracranial aneurysm pathogenesis: a multi-omics and machine learning study.

Journal: BMC neurology

Published: April 20, 2025

Showing 1-12 of 105

Last Updated: 09/26/2026