Lukas Balek

Brno, JM, Czech Republic

Last Updated: 09/26/2026

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Found 16 publications

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.

Journal: EMBO molecular medicine

Published: November 10, 2019

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase.

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 21, 2019

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.

Journal: Science signaling

Published: September 20, 2018

Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals.

Nanodiamonds as "artificial proteins": Regulation of a cell signalling system using low nanomolar solutions of inorganic nanocrystals.

Journal: Biomaterials

Published: November 08, 2017

Computer-assisted engineering of hyperstable fibroblast growth factor 2.

Computer-assisted engineering of hyperstable fibroblast growth factor 2.

Journal: Biotechnology and bioengineering

Published: September 14, 2017

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Journal: Oncotarget

Published: August 01, 2017

Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome.

Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome.

Journal: Cellular signalling

Published: May 05, 2017

ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3.

ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3.

Journal: Bone

Published: December 17, 2016

Statins do not inhibit the FGFR signaling in chondrocytes.

Statins do not inhibit the FGFR signaling in chondrocytes.

Journal: Osteoarthritis and cartilage

Published: November 04, 2016

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

Journal: eLife

Published: September 14, 2016

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.

An inactivating mutation in intestinal cell kinase, ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome.

Journal: Human molecular genetics

Published: June 27, 2016

Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.

Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.

Journal: Human molecular genetics

Published: October 17, 2015

Showing 1-12 of 16

Last Updated: 09/26/2026