Lukas Tenora

Prague, PR 16000, Czech Republic

Last Updated: 09/26/2026

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Found 29 publications

Microglial-Targeted GCPII Inhibition Reverses Neurocognitive Impairment and Synaptic Loss After EcoHIV Infection.

Microglial-Targeted GCPII Inhibition Reverses Neurocognitive Impairment and Synaptic Loss After EcoHIV Infection.

Journal: Cells

Published: January 30, 2026

A Star-PEGylation Strategy to Improve Testosterone Pharmacokinetics.

A Star-PEGylation Strategy to Improve Testosterone Pharmacokinetics.

Journal: Molecules (Basel, Switzerland)

Published: November 25, 2025

Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits.

Inhibition of microglial glutaminase alleviates chronic stress-induced neurobehavioral and cognitive deficits.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Published: May 13, 2025

Discovery of Orally Available Prodrugs of Itaconate and Derivatives.

Discovery of Orally Available Prodrugs of Itaconate and Derivatives.

Journal: Journal of medicinal chemistry

Published: January 23, 2025

Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs.

Pharmacokinetic Evaluation of Neutral Sphinghomyelinase2 (nSMase2) Inhibitor Prodrugs in Mice and Dogs.

Journal: Pharmaceutics

Published: December 09, 2024

Therapeutic resurgence of 6-diazo-5-oxo-l-norleucine (DON) through tissue-targeted prodrugs.

Therapeutic resurgence of 6-diazo-5-oxo-l-norleucine (DON) through tissue-targeted prodrugs.

Journal: Advances in pharmacology (San Diego, Calif.)

Published: July 21, 2024

Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery.

Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery.

Journal: Journal of medicinal chemistry

Published: November 10, 2023

Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice.

Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice.

Journal: Pharmaceutics

Published: August 11, 2023

A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis.

A gut-restricted glutamate carboxypeptidase II inhibitor reduces monocytic inflammation and improves preclinical colitis.

Journal: Science translational medicine

Published: August 09, 2023

Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold.

Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold.

Journal: European journal of medicinal chemistry

Published: May 10, 2023

The combination of immunotherapy and a glutamine metabolism inhibitor represents an effective therapeutic strategy for advanced and metastatic murine pancreatic adenocarcinoma.

The combination of immunotherapy and a glutamine metabolism inhibitor represents an effective therapeutic strategy for advanced and metastatic murine pancreatic adenocarcinoma.

Journal: International immunopharmacology

Published: January 11, 2023

Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.

Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.

Journal: Science advances

Published: November 16, 2022

Showing 1-12 of 29

Last Updated: 09/26/2026