Luke J. O'neill

152-160 Pearse Street, D02 R590
Dublin, L, Ireland

Last Updated: 09/26/2026

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Found 252 publications

Living in the age of inflammation: the reverse hygiene hypothesis.

Living in the age of inflammation: the reverse hygiene hypothesis.

Journal: Nature reviews. Immunology
Published: August 20, 2026

Pyruvylation of STAT1 inhibits anti-viral immunity: Prospects for new anti-viral therapeutics.

Pyruvylation of STAT1 inhibits anti-viral immunity: Prospects for new anti-viral therapeutics.

Journal: Molecular cell
Published: April 24, 2026

Retraction Note: MAVS is a sensor of fumarate during antiviral immunity.

Retraction Note: MAVS is a sensor of fumarate during antiviral immunity.

Journal: Nature microbiology
Published: April 01, 2026

SDH inhibition quenches rheumatoid arthritis flare-associated IL-1β+IFN-γ+ macrophages via NF-κB/STAT4.

SDH inhibition quenches rheumatoid arthritis flare-associated IL-1β+IFN-γ+ macrophages via NF-κB/STAT4.

Journal: Annals of the rheumatic diseases
Published: January 28, 2026

4-Octyl itaconate blocks STAT3-induced ACE2 expression to reduce uptake of SARS-CoV-2.

4-Octyl itaconate blocks STAT3-induced ACE2 expression to reduce uptake of SARS-CoV-2.

Journal: Biochemical pharmacology
Published: January 28, 2026

Mitochondria target the plasma membrane to cause mitoxyperiosis.

Mitochondria target the plasma membrane to cause mitoxyperiosis.

Journal: Cell research
Published: January 13, 2026

Immunometabolites and cancer: the role of 2-hydroxyglutarate, succinate, fumarate and itaconate in tumour development and anti-tumour immunity.

Immunometabolites and cancer: the role of 2-hydroxyglutarate, succinate, fumarate and itaconate in tumour development and anti-tumour immunity.

Journal: Immunology letters
Published: December 24, 2025

Adenosine 2A receptor-dependent activation of AMPK represses TH17 cell pathogenicity through epigenetic and metabolic reprogramming.

Adenosine 2A receptor-dependent activation of AMPK represses TH17 cell pathogenicity through epigenetic and metabolic reprogramming.

Journal: Science signaling
Published: September 23, 2025

Mitochondrial glutathione transporter SLC25A40 regulates macrophage cytokine production.

Mitochondrial glutathione transporter SLC25A40 regulates macrophage cytokine production.

Journal: Scientific reports
Published: July 31, 2025

Targeting complex IV to alter the tumor microenvironment and boost macrophage antitumor immunity.

Targeting complex IV to alter the tumor microenvironment and boost macrophage antitumor immunity.

Journal: Life metabolism
Published: July 28, 2025

Lessons from Glucocorticoids, Metformin, and Dimethyl Fumarate: Could Targeting Immunometabolism Lead to Better Anti-Inflammatory Therapies?

Lessons from Glucocorticoids, Metformin, and Dimethyl Fumarate: Could Targeting Immunometabolism Lead to Better Anti-Inflammatory Therapies?

Journal: Annual review of pharmacology and toxicology
Published: July 09, 2025

Rift Valley fever and invisible women.

Rift Valley fever and invisible women.

Journal: Research directions. One health
Published: June 04, 2025
Showing 1-12 of 252

Last Updated: 09/26/2026